羊水过少与病理妊娠的相关性及对围生结局的影响  

Correlation between oligohydramnios with pathological pregnancy and the affections on perinatal outcome

作　　者：陈海霞[1] 李善凤[1] 骆秀翠[1] 

机构地区：[1]连云港市妇幼保健院产科,连云港222006

出　　处：《现代预防医学》2013年第9期1649-1651,1653,共4页Modern Preventive Medicine

摘　　要：目的探讨妊娠晚期羊水过少与其他病理妊娠的相关性,以及对围生结局的影响。方法收集2008年01月～2010年12月某院分娩的妊娠晚期羊水过少孕妇680例作为实验组。随机抽取同期该院分娩的妊娠晚期羊水量正常孕妇600例作为对照组,两组病例就合并其他病理妊娠、围生结局进行比较。结果实验组中胎儿生长受限(fetal growth restriction FGR)、妊娠期高血压疾病、过期妊娠的发生率均较对照组高,差异有统计学意义(P﹤0.01);胎儿畸形的发生率较对照组不高,差异无统计学意义(P﹥0.05)。实验组中同时合并其他两种、3种病理妊娠的发生率均较对照组高,差异有统计学意义(P﹤0.01);胎儿窘迫、羊水污染、新生儿窒息率也明显升高,差异有统计学意义(P﹤0.05,P﹤0.01)。合并其他病理妊娠的羊水过少孕妇,其胎儿窘迫、羊水污染、新生儿轻度窒息率远较不合并其他病理妊娠的孕妇高,差异有统计学意义(P﹤0.05,P﹤0.01)。结论羊水过少与其他病理妊娠密切相关,它威胁围产儿的生命;如果合并其他病理妊娠,则围生儿风险增大;羊水过少可作为胎儿生长受限、妊娠期高血压疾病、过期妊娠时胎儿的危险信号。OBJECTIVCE To investigate the correlation between third trimester oligohydramnios with the pathological pregnancy and the affections on perinatal outcome.METHODS The clinical data of 680 patients with oligohydranmios in our hospital from January 2008 to December 2010 were collected as experimental group.600 patients over the same period with normal amniotic fluid volume were selected randomly as a control group.Two groups of patients were compared on the combined pathology of pregnancy and perinatal outcomes.RESULTS The incidence of fetal growth restriction（FGR）,hypertensive disorders in pregnancy and postterm pregnancy of experimental group were higher than the control group,the difference was statistically significant（P﹤0.01）;the incidence of fetal malformations was not high compared with the control group,the difference was not statistically significant（P﹥0.05）.The incidences of two or three kinds of pregnancy complications in experimental group were significantly higher than that of control group,the difference was statistically significant（P﹤0.05,P﹤0.01）.The incidences of fetal distress,amniotic and perinatal mortality were significantly higher,the difference was statistically significant（P﹤0.05,P﹤0.01）.Fetal distress,amniotic and mild neonatal asphyxia rates of oligohydramnios pregnant women with pathological pregnancy were higher than those women without pathological pregnancy,the difference was statistically significant（P﹤0.05,P﹤0.01）.CONCLUSION Oligohydramnios is closely related with the pathological pregnancy and it threatens the lives of perinatal infants;the risk of the perinatal child will increase combined pathology of pregnancy.Oligohydramnios can be considered a danger signal in FGR,hypertensive disorders in pregnancy and postterm pregnancy.

关 键 词：羊水过少 病理妊娠 围生结局 

分 类 号：R714.2[医药卫生—妇产科学]