新沂市成年人群乙型肝炎病毒血清流行病学调查  

Serum epidemiological investigation on HBV of adult populations in Xinyi City

作　　者：孙光卫[1] 张艺飓[2] 胡传强[1] 耿丽娜[1] 李现勇[1] 

机构地区：[1]新沂市疾病预防控制中心,新沂221400 [2]江苏省疾病预防控制中心

出　　处：《现代预防医学》2013年第9期1741-1742,1748,共3页Modern Preventive Medicine

摘　　要：目的为进行乙型肝炎疫苗临床试验,了解新沂市成年人群乙型肝炎感染情况,制定该市乙肝防制策略提供依据。方法选取两个镇,调查20～60岁的成年人1480名,采用ELISA法检测血清中HBV标志物。结果新沂市成年人群HBsAg阳性率为5.27%,HBV感染率为75.68%。检出15种HBV感染模式,有16.62%人群(模式9)为乙肝疫苗临床试验目标对象。结论调查结果揭示了新沂市乙型肝炎病毒感染在成年人群中感染的流行病学特征,为疫苗临床试验和乙肝防制策略提供了背景基础资料和科学依据。OBJECTIVE In order to conduct clinical research of hepatitis B virus（HBV）and grasp the infection distribution of HBV for adult populations in Xinyi city,formulate the strategy for prevention and control.METHODS The total 1 480 serum samples of adult populations whose ages were 20 to 60 years old in two towns were tested,used ELISA assay for the detection of serum HBV markers.RESULTS In adult populations,the postive rate of HBsAg was 5.27%.The infection rate of HBV was 75.68%.There were 15 types of HBV markers in all HBV infections.There were 16.62% of population（type 9）for objects of clinical test of hepatitis B vaccine.CONCLUSION The survey results reveal the hepatitis B virus infection of epidemiological charaxteristics for adult populations in Xinyi city,it provides a background information and scientific basis for clinical research on vaccines and the strategy for prevention and control.

关 键 词：乙型肝炎病毒 感染 血清流行病学 

分 类 号：R181.36[医药卫生—流行病学] R373.21[医药卫生—公共卫生与预防医学]