Differentially-expressed opsin genes identified in Sinocyclocheilus cavefish endemic to China  

作　　者：Fanwei MENG Yahui ZHAO John H. POSTLETHWAIT Chunguang ZHANG 

机构地区：[1]Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China [2]Institute of Neuroscience, University of Oregon, Eugene, OR 97403, USA

出　　处：《Current Zoology》2013年第2期170-174,共5页动物学报（英文版）

摘　　要：Eye degeneration is a common troglomorphic character of cave-dwelling organisms. Comparing the morphology and molecular biology of cave species and their close surface relatives is a powerful tool for studying regressive eye evolution and other adaptive phenotypes. We compared two co-occurring and closely-related species of the fish genus Sinocyclocheilus, which is endemic to China and includes both surface- and cave-dwelling species. Sinocyclocheilus tileihornes, a cave species, had smaller eyes than Sinocyclocheilus angustiporus, a surface species. Histological and immunohistochemical analyses revealed that the cave- fish had shorter cones and more disorderly rods than did the surface-dwelling species. Using quantitative PCR and in situ hybri- dization, we found that rhodopsin and a long-wavelength sensitive opsin had significantly lower expression levels in the cavefish. Furthermore, one of two short-wavelength-sensitive opsins was expressed at significantly higher levels in the cavefish. Changes in the expression ofopsin genes may have played a role in the degeneration of cavefish eyes [Current Zoology 59 （2）： 170-174, 2013].

关 键 词：SINOCYCLOCHEILUS CAVEFISH Eye Retina Opsin. 

分 类 号：Q959.4[生物学—动物学] S965.9[农业科学—水产养殖]