Dual roles of Hh signaling in the regulation of somatic stem cell self-renewal and germline stem cell maintenance in Drosophila testis  

作　　者：ZhaoZhang  XiangdongLv  JinJiang  LeiZhang YunZhao 

机构地区：[1]State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China[2]Department of Developmental Biology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA

出　　处：《Cell Research》2013年第4期573-576,共4页细胞研究（英文版）

摘　　要：Dear Editor, Stem cell niche is a specialized microenvironment crucial for stem cell self-renewal. Drosophila testis con- tains two types of stem cells： germline stem cells （GSCs） and somatic cyst stem cells （CySCs）, providing a good model for studying niche-stem cell interaction [1]. At the apex of testis tube, non-mitotic somatic cells form a tightly folded structure called the hub. About 10 GSCs,

关 键 词：成体干细胞 生殖干细胞 自我更新 睾丸 果蝇 调控 信号 相互作用 

分 类 号：Q813[生物学—生物工程] N1[自然科学总论]