盆炎清胶囊的质量标准研究  

Quality standard study of Penyanqing capsule

作　　者：陈通[1] 梁秀群[1] 陈勇[2] 胡丰[2] 曾萍[2] 刘瑛丽[2] 杨晨[2] 

机构地区：[1]广西中医学院附属瑞康医院,南宁市530000 [2]广西中医学院药学院,南宁市530001

出　　处：《临床合理用药杂志》2013年第10期51-53,共3页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的建立盆炎清胶囊的质量控制方法。方法用薄层色谱法(TLC)对盆炎清胶囊中的黄柏、赤芍、牡丹皮、紫花地丁进行定性鉴别;采用高效液相色谱法(HPLC)测定胶囊中芍药苷的含量。结果 TLC色谱图中斑点清晰,易于识别;芍药苷在0.224～1.120μg之间与峰面积呈良好的线性关系,r=0.9999,平均回收率为100.83%,RSD为1.04%。结论 TLC联合HPLC控制盆炎清胶囊的质量标准,方法简便,灵敏度高,重现性好,可用于该制剂的质量控制。Objective To establish the quality standard of Penyanqing capsule. Methods To identify cortex phello- dendrl chinensis and radix paeonlae rubra and cortex moutan and herba violae by TLC qualitatively. Determine peoniflofin in capsule by HPLC. Results TLC chromatogram spots were dear and easy to identify;Paeoniflorin and peak area showed a good linear relationship between 0. 224 - 1. 120μg,r = 0.9999, average recovery rate of peoniflorin was 100. 83%, RSD was 1.04%. Conclusion The method is simple,accurate and can be used for the quality control of the granules.

关 键 词：盆炎清胶囊 薄层色谱法 高效液相色谱法 芍药苷 

分 类 号：R286[医药卫生—中药学]