纳洛酮在抗休克中的临床应用  

Clinical application of naloxone in antishock

作　　者：曾广金 

机构地区：[1]广东省茂名农垦医院神经内科,广东高州525200

出　　处：《中国当代医药》2013年第11期70-71,共2页China Modern Medicine

摘　　要：目的探讨纳洛酮在抗休克中的临床疗效。方法选择2009年12月～2012年12月本院收治的休克患者54例,将其分为治疗组28例,对照组26例。在病因治疗和抗休克的基础上,治疗组加用纳洛酮静滴,对照组不用。观察并比较两组死亡率、血压回升时间、末梢循环好转时间及开始排尿时间。结果治疗组的死亡率明显低于对照组;治疗组血压回升时间、末梢循环开始好转时间及开始排尿时间较短的患者比例均明显高于对照组(P<0.01或P<0.05)。结论纳洛酮能明显提高抗休克的疗效。Objective To discuss the clinical effects of naloxone in antishock. Methods 54 cases of patients with shock in our hospital from December 2009 to December 2012 were selected, and divided into the treatment group （n = 28） and the control group （n = 26）. On the basis of etiological treatment and antishock, patients in the treatment were given naloxone by static drop, patients in the control group were not given it. The mortality rate, time of blood pressure in- creasing, peripheral circulation improvement and micturition of the two groups were observed and compared. Results The mortality rate in the treatment group was significantly lower than the control group, the proportions of patients with shorter time of blood pressure increasing, peripheral circulation improvement and micturition in the treatment group were more than those in the control group （P 〈 0.05 or P 〈 0.01）. Conclusion Naloxone can significantly improve the clinical effect of antishock.

关 键 词：纳洛酮 抗休克 血压回升 末梢循环好转 排尿 

分 类 号：R972.5[医药卫生—药品]