影响尖锐湿疣复发的危险因素分析及干预对策  

Risk factors for condyloma acuminatum recurrence and intervention measures

作　　者：张东兴[1] 刘诗[1] 刘雄[1] 姚明珠[1] 赖洪涛[1] 

机构地区：[1]梅州市人民医院皮肤科,广东梅州514023

出　　处：《中国性科学》2013年第4期41-44,共4页Chinese Journal of Human Sexuality

摘　　要：目的:分析尖锐湿疣(CA)复发的危险因素,并探讨相应的干预对策。方法:回顾自2006年6月份以来,入我院治疗的尖锐湿疣(CA)患者的资料,对患者的一般情况如性别、年龄、婚姻情况及受教育程度,个人行为如饮酒、吸烟、熬夜情况、野游史、安全套的使用情况、传染性伴侣的情况,患者的皮损发生部位、范围、颜色、数目、感染HPV病毒的亚型、复发的情况,采用卡方检验、单因素非条件Logistic回归分析和多因素非条件Logistic回归分析,模型筛选采用Step-wise法,评价影响尖锐湿疣复发的危险因素。结果:显示嗜酒(OR=1.769,95%CI:1.420-2.115)、熬夜(OR=6.447,95%CI:1.826-22.769)、皮损发生在肛周(OR=0.863,95%CI:0.709-1.051)、皮损HPV型别为16型(OR=1.539,95%CI:1.042-2.635)、皮损HPV型别为复合型(OR=3.640,95%CI:2.169-6.193)等是尖锐湿疣(CA)复发的主要促进因素。结论:针对尖锐湿疣(CA)复发的危险因素,我们提出了尖锐湿疣(CA)患者应注意禁止饮酒、不熬夜;在肛周,治疗时的物理疗法,深度要达到疣体的底,范围要大于疣体。Objectives： To analyze the risk factors for the recurrence of condyloma acuminatum （CA）, and to explore the intervention of the corresponding countermeasures. Methods： A retrospective review was made on the clinical data of patients who were admitted into our hospital since June 2006. We investigated the patient＇ s general condition such as gender, age, marriage status and the education level, individual behaviors such as drinking, smoking, staying up late, wild tour history, condom use situation, the condition of infectious partners, a patient＇s skin location, range, color, number, infection of HPV virus subtype, recurrent circumstance. The data were analyzed by using the chi - square test, single factor unconditional logistic regression anal-ysis and multiple factors unconditional Logistic regression analysis. Results： The results indicated that the risk factors for CA re-currence include drinking （ OR = 1. 769, 95% CI： 1. 420 -2. 115） , staying up late （ OR =6. 447, 95% CI： 1. 826-22. 769）, lesions occurring in crissum （ OR =0. 863, 95% CI： 0. 709 - 1. 051 ） , lesions HPV type 16 （ OR = 1. 539, 95% CI： 1. 042 - 2. 635）, lesions HPV complex type （ OR = 3. 640, 95% CI ： 2. 169 - 6. 193 ）. Conclusion： We suggest that CA patients should stay away from the risk factors for condyloma acuminatum by having alcohol control, going to bed early and applying physical ther-apy to the depth of wart body.

关 键 词：尖锐湿疣(CA) 危险因素 复发 干预对策 

分 类 号：R752.53[医药卫生—皮肤病学与性病学]