老年冠心病患者血清Zn、Cu、Fe、Cr的测定及临床意义  

Determination of Zn、Cu、Fe、Cr levels in elderly patients with coronary heart disease

作　　者：周晓钢[1] 周景春[2] 高学文[2] 叶继诚[1] 

机构地区：[1]内蒙古医学院生物化学教研室,呼和浩特市010059 [2]内蒙古自治区医院

出　　处：《心血管康复医学杂志》2000年第2期18-20,共3页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的 :探讨老年冠心病与血清锌 (Zn)、铜 (Cu)、铁 (Fe)及铬 (Cr)的关系及其临床意义。方法 :用日本岛津 AA176型原子吸收分光光度计 ,对 81例老年冠心病患者及 6 5例老年对照组测定了血清 Zn、Cu、Fe及 Cr的含量。结果 :老年冠心病患者血清 Zn、 Fe水平明显高于老年对照组。而老年冠心病组血清 Cu水平显著低于老年对照组。老年冠心病组血清 Cr和 Cu/Zn水平明显低于对照组。结论 :高 Zn、Fe,低 Cu、Cr与冠心病的发生发展有密切关系。Objective:The objective of this study was to evaluate the relationship between the levels of serum zinc(Zn) 、copper(Cu)、iron(Fe)、chromium(Cu) and coronary heart disease (CHD)in elderly.Methods:The serum levels of Zn、Cu、Fe and Cr of 81 cases elderly patients with CHD and 65 cases control subjects were determined by atomic absorption spectrum(AAS).Results:The serum Zn、Fe levels of the elderly patients with CHD were higher than the control subjects; The serum Cu level of CHD was significantly lower than the control subjects; The level of Cr and Cu/Zn from the patients with CHD were lower compared with control subjects.Conclusion:The higher levels of serum Zn、Fe and lower levels of serum Cu、Cr are risk factors of CHD on elderly. The results of this study suggeste if decrease level of Zn and increase level of Cu in the diet of elderly, there are significance for CHD prevention and cure. Author′s address Department of biochemistry Inner Mongolia College Huhehote,010059

关 键 词：冠心病 微量元素 老年人 

分 类 号：R541.402[医药卫生—心血管疾病]