中药内服、外洗并联合抗组胺药物治疗慢性肾功能不全非透析患者瘙痒症状随机对照研究  

Randomized Controlled Trail on Internal and External Application of TCM Drugs Combined with Antihistamine in Treatment of Non-Dialysis Patients With Chronic Renal Failure and Pruritus

作　　者：陈肖蓉 孔祥栋 

机构地区：[1]富阳市人民医院肾内科,浙江杭州311400

出　　处：《中华中医药学刊》2013年第5期1215-1216,共2页Chinese Archives of Traditional Chinese Medicine

摘　　要：目的:探讨中药内服、外洗并联合抗组胺药物治疗慢性肾功能不全非透析患者瘙痒的疗效。方法:选择90例慢性肾功能不全合并皮肤瘙痒症的患者,随机分为3组,每组30例,A组予抗阻胺药物治疗,B组予中药内服、外洗治疗,C组患者予中药内服、外洗联合抗组胺药物治疗,观察三组患者治疗前后生化指标及皮肤瘙痒缓解程度的变化。结果:治疗后C组瘙痒程度积分明显低于其他两组(P<0.05);C组的BUN、P、iPTH水平的下降以及Ca上升的改善均较A组、B组高,B组较A组高,且差异有统计学意义(P均<0.05)。结论:中药内服、外洗加药物口服治疗慢性肾功能不全伴有瘙痒患者,能明显减轻瘙痒症状。Objective：To explore the effect of traditional Chinese medicine combined with external washing and antihistamine in non-dialysis patients with chronic renal failure（CRF） and pruritus.Methods：90 non-dialysis patients with CRF and pruritus were divided into three groups randomly,patients in group A were treated with antihistamine,and group B with traditional Chinese medicine combined with external washing,group C with traditional Chinese medicine combined with external washing and antihistamine.The biochemical index and relieved degree of pruritus were observed.Results：The degree score of pruritus was lower in group C than that in group A and B（P0.05）.The levels of Scr,BUN,Ca,P and iPTH in Group C was better than those in group A and B.Group B was better than group A（P0.05）.Conclusion：The treatment of traditional Chinese medicine combined with external washing and antihistamine can significantly relieve the pruritus in patients with CRF and pruritus.

关 键 词：慢性肾功能不全 瘙痒 中药 

分 类 号：R692.5[医药卫生—泌尿科学]