肠球菌致尿路感染的现状研究  

Investigation of Enterococcus causing urinary tract infection

作　　者：陆明钢[1,2] 董学君[2] 王颖[2] 

机构地区：[1]温州医学院,浙江温州325000 [2]绍兴市人民医院临床检验中心,浙江绍兴312000

出　　处：《中国微生态学杂志》2013年第4期409-411,共3页Chinese Journal of Microecology

基　　金：绍兴市人民医院临床检验中心为省市共建重点学科(GJSX-010-003)

摘　　要：目的监测肠球菌在住院患者尿路感染中的地位及耐药性,为临床疾病防控和用药提供切实可行的方法。方法采用回顾性分析,对近年医院尿路感染患者进行调查研究。结果尿液培养分离的2 193株病原菌中,肠球菌占11.8%,其中以粪肠球菌为主,占59.7%,屎肠球菌占39.1%,鹑鸡肠球菌占1.2%;在耐药性方面,体外药敏试验显示两种肠球菌表现各异,屎肠球菌对抗菌药物的敏感性普遍比粪肠球菌高,但是两种肠球菌对糖肽类及替加环素都表现出100%的敏感。结论院内尿路感染患者中11.8%是由肠球菌引起,仅次于大肠埃希菌占第二位;肠球菌对抗生素的耐药性较严重,临床在治疗尿路感染时应合理选用药物。Objective To monitor the drug resistances of Enterococcus causing urinary tract infection in order to provide a practical method for the disease control and clinical drug use.Methods Patients with urinary tract infection were investigated by using retrospective method.Results In the 2,193 isolated pathogen strains,Enterococci accounted for 11.8%,among which E.faecalis,E.faecium and E.gaillinarum accouonted for 59.7%,39.1% and 1.2% respectivly.The results of susceptibility test showed E.faecium had a higher sensitivity than E.faecalis,but the two kinds of Enterococci showed 100% sensitivity rate to glycopeptides and Tigecycline.Conclusion The nosocomial urinary tract infection caused by Enterococcus accounted for 11.7%,next only to Escherichia coli.The drug resistance of Enterococcus is high.Antibiotics should be used reasonably for urinary tract infection treatment in clinical practice.

关 键 词：尿路感染 肠球菌 耐药性 

分 类 号：R378.1[医药卫生—病原生物学]