流感病毒热稳定性的研究进展  

Advances in research on thermostability of influenza virus

作　　者：年庆功[1] 姜涛[1] 秦鄂德[1] 秦成峰[1] 

机构地区：[1]军事医学科学院微生物流行病研究所,病原微生物生物安全国家重点实验室,北京10007

出　　处：《军事医学》2013年第3期231-233,共3页Military Medical Sciences

基　　金：国家自然科学基金资助项目(81000722)

摘　　要：热稳定性是流感病毒的固有生物学特性,主要由病毒的血凝素蛋白决定,并且与环境温度、pH、盐度、空气湿度和界面性质等理化因素密切相关,在病毒进化与传播过程中发挥重要作用。热稳定性的具体机制目前尚不确定。流感病毒热稳定性的研究将有助于加深对流感病毒结构与功能关系的认识。本文综述了流感病毒热稳定性的研究进展。Thermostability is an inherent biological characteristic of influenza virus and plays a great role in the evolution and transmission of virus. The thermostability of influenza virus is determined by hemagglutinin（ HA）, and by many physico- chemical factors, such as environment temperature, pH, salinity, humidity and surface characteristics. However, the exact mechanism of thermostability remains unknown. Researches focused on influenza virus thermostability will shed light on the relationship between viral structure and functions and help to prepare for influenza pandemics. The recent advances in ther-mostability of influenza virus are briefly reviewed.

关 键 词：流感病毒 热稳定性 传播 

分 类 号：R373[医药卫生—病原生物学]