钛氢化物催化黄樟油素异构化的研究  

STUDIES ON ISOMERIZATION OF SAFROLE CATALYZED BY TITANO-HYDROGEN COMPLEXES

作　　者：玄镇爱[1] 刘以寅[1] 荣建辉 王者福[1] 陈寿山[1] 

机构地区：[1]南开大学元素有机化学研究所,天津300071

出　　处：《Chinese Journal of Catalysis》1991年第1期59-64,共6页催化学报（英文）

基　　金：国家自然科学基金

摘　　要：以(RCp_2TiCl_2/i-PrMgBr体系催化黄樟油素异构化,得到了高收率、高选择性的反式异黄樟油素,从而提供了一种新的异黄樟油素的合成方法。详细研究了影响反应的各种因素。通过ESR等手段对反应机理进行了探索并提出了设想。The isomerization of safrole catalyzed by (RCp)2TiCl2/i-PrMgBr system was studied and frans-isosafrole was obtained with high yield and high selectivity, thus, a new synthetic method of isosafrole was suggested. Various factors,such as solvent,reaction temperature, catalyst amount and R group in (RCp)2TiCl2, affecting the safrole isomerization were studied and discussed.The reaction mechanism was tracked by ESR method and a tentative mechanism was proposed.

关 键 词：黄樟油素 异构化 钛氢化物 催化 

分 类 号：TQ651.1[化学工程—精细化工]