白芍总甙对慢性荨麻疹患者辅助T细胞和复发率的影响研究  

Effect of Total Glucosides of Paeonia on Auxiliary T Cells and Relapse Rate of Patients with Chronic Urticaria

作　　者：李平[1] 李世根[1] 刘永刚[1] 张国祥[1] 谢少玲[1] 

机构地区：[1]武警广东省总队医院药剂科,广东广州510507

出　　处：《今日药学》2013年第3期135-137,共3页Pharmacy Today

基　　金：广东省医院药学研究基金--朗生免疫专项(编号:2011L04)

摘　　要：目的观察白芍总甙对慢性荨麻疹患者辅助T细胞和复发率的影响。方法选择99例慢性荨麻疹患者随即分为对照组和治疗组,2组连续4周口服氯雷他定片10 mg/d,治疗组同时口服白芍总苷胶囊600 mg,2次/日,连续服用12周。对照组服用安慰剂,服用方法同白芍总苷胶囊。观察患者CU的有效率、复发率及IgE的变化。结果治疗组12周后,慢性荨麻疹患者的复发率比对照组降低18.7%及IgE值降低0.22±0.02。结论白芍总甙可以调节部分慢性荨麻疹患者T细胞功能,可以降低慢性荨麻疹复发率。Objective To observe the effect of total glucosides of paeonia （TGP） on auxiliary T cells and the relapse rate in patients with chronic urticaria. Methods A total of 99 cases chronic urticaria （CU） patients were randomly divided into the control group and treatment group. Patients in the 2 groups, take loratadine tablets 10 mg/d, of 4 consecutive weeks in oral. Patients in the treatment group were also treated with total glucosides of peony capsule 600 mg 2 times/d, for 12 weeks. Patients in the control group were given placebo. Results After 12 weeks, relapse rate of CU patients in the treatment group was lowered by 18.7% and IgE levels reduced by 0.22 ± 0.02, compared with that of the control group. Conclusion The TGP can adjust some CU patients T cell function and reduce the CU recurrence rate.

关 键 词：白芍总甙 慢性荨麻疹 T细胞 复发率 

分 类 号：R97[医药卫生—药品]