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作 者:李桂侠[1] 洪兰[1] 林颖娜[1] 李涛[1] 黄艳影[1] 刁倩[1] 吕学玉[1] 杜辉[1] 汪卫东[1]
机构地区:[1]中国中医科学院广安门医院心理科,北京100053
出 处:《世界中医药》2013年第4期378-381,共4页World Chinese Medicine
基 金:"十一五"国家科技支撑计划重点项目(编号:2009BAI77B09);国家自然科学基金资助项目(编号:81072854)
摘 要:目的:观察TIP睡眠调控技术联合西药治疗原发性失眠症的临床疗效。方法:将符合入组标准的70例原发性失眠症患者随机分为TIP联合西药组和西药组,每组35例。西药组于睡前半小时给予艾司唑仑片1~2片,TIP联合西药组在服用艾司唑仑片基础上配合每周两次TIP睡眠调控技术治疗,观察治疗前后匹兹堡睡眠质量指数量表(PSQI)变化,观察周期4周。结果:组内比较,TIP联合西药组,PSQI总分、睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍、日间功能改善有统计学意义(P<0.05)。西药组,PSQI总分、睡眠质量、睡眠时间改善有统计学意义(P<0.05)。组间比较,治疗后两组间疗效比较,PSQI总分、睡眠质量、催眠药物、日间功能有统计学意义(P<0.05),TIP联合西药组优于西药组。治疗前和治疗后的差值比较,PSQI总分、睡眠质量、入睡时间、催眠药物、日间功能两组有统计学意义(P<0.05),TIP联合西药组优于西药组。有效率比较,TIP联合西药组总有效率为72%,西药组的总有效率为29%。结论:本研究提示两种干预方法对原发性失眠症的改善程度不同,TIP联合西药组优于单纯艾司唑仑组,这提示在初始治疗阶段心理治疗联合药物是治疗失眠症更为有效的方案。Objective: To observe the curative effect of Sleep-regulating Technique (TIP3-2) combined with western medicine in treating primary insomnia using. Methods:The included 70 patients suffered from primary insomnia were randomly and evenly divided into two groups, TIP combined with drugs group and drug only group. The patients in drug only group were given 1 to 2 tablets Estazolam half an hour before sleep. Apart from taking Estazolam, the patients in TIP combined with drugs group were given extra Sleep-regulating Tech- nique treatment twice a week. The changes of Pittsburgh sleep quality index (PSQI) before and after treatment were observed. The ob- servation period was 4 weeks. Results: Comparison within eaehgroup : In TIP combined with drugs group, there were significant improve- ment in total score of PSQI, subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbances, use of sleeping medication, and daytime dysfunction ( P 〈 0. 05 ). In drug only group, the total score of PSQI, subjective sleep quality, sleep duration also showed significant improvement ( P 〈 0. 05 ) ; Comparison between the two groups : Comparing the data after treatment, there were significant differences in the total score of PSQI, subjective sleep quality, medication use and daytime dysfunction (P 〈 0. 05 ). TIP combined with drugs group showed better improvement than drug only group. Comparing the difference of values before and after treatment, there were significant difference between the two groups in the total score of PSQI, subjective sleep quality, sleep laten- cy, medication use and daytime dysfunction ( P 〈 0. 05 ). TIP combined with drugs group showed better improvement than drug only group. The total effective rate in TIP combined with drugs group was 72% , while that in drug only group was 29%. Conclusion:The two methods have different degrees of improvement in treating primary insomnia. TIP combined with western medication is better than only
分 类 号:R163[医药卫生—公共卫生与预防医学]
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