活血通经消瘀巴布剂组方药物木芙蓉叶等乙醇提取工艺研究  

Study on Ethanol Extraction Technology on Components of Huoxue Tongjing Xiaoyu Cataplasma Such as Cottonrose Hibiscus Leaf

作　　者：杨一丁[1] 张伟 杨文婷[3] 高文勇 

机构地区：[1]青岛市市立医院,青岛266071 [2]青岛市海慈医疗集团,青岛266033 [3]山东中医药大学药学院,济南250355 [4]青岛四方嘉兴路街道人民路社区卫生服务站,青岛266033

出　　处：《世界中医药》2013年第4期450-452,共3页World Chinese Medicine

基　　金：山东省2009-2010年度中医药科技发展计划项目(编号:2009-201)

摘　　要：目的:研究活血通经消瘀巴布剂组方药物的乙醇提取工艺。方法:采用正交设计法,以醇浸物和大黄素的含量为考察指标优选醇提取工艺。结果:最佳提取工艺为用浓度为60%的乙醇,提取3次,每次乙醇用量为药材重量的6倍,每次提取时间为40min。结论:优选的活血通经消瘀巴布剂组方药物的乙醇提取工艺稳定可行。Objective： To study ethanol extraction of components of Huoxue tongjing xiaoyu cataplasma. Methods ： By orthogonal design, the ethanol extraction process was optimized with the yield of the contents of alcohol extracts and emodin as indexes. Results：The opti- mum alcohol extraction process was obtained with 60% alcohol, extracting twice for 40 minutes, and the amount of ethanol was six times over the weight of the herbal. Conclusion：The optimum extraction process of Huoxue tongjing xiaoyu cataplasma by orthogonal design is stable and feasible.

关 键 词：醇浸物 大黄素 高效液相色谱法 正交设计 

分 类 号：R284.1[医药卫生—中药学]