甘草及其有效成分的皮肤药理和临床应用  

Dermatopharmacology and clinic application of Glycyrrhizae Radix et Rhizoma and its active components

作　　者：张明发[1] 沈雅琴[1] 张艳霞 

机构地区：[1]上海美优制药有限公司,上海201422 [2]青岛即墨市食品药品监督管理局,山东即墨266200

出　　处：《药物评价研究》2013年第2期146-156,共11页Drug Evaluation Research

摘　　要：近年来临床上正在试用甘草及其有效成分的制剂治疗各种皮肤病,包括过敏性紫癜、银屑病、湿疹、玫瑰糠疹、荨麻疹、系统性红斑狼疮、小儿丘疹性肢端皮炎样皮疹、带状疱疹、扁平疣、斑秃、白癜风和皮肤色素沉着等。综述甘草提取物及其黄酮类化合物、甘草酸等对变态反应性皮肤病、皮肤肿瘤、病毒性皮肤病、色素沉着等皮肤病的药理作用和临床应用研究进展。In recent years, in clinic the preparations of Glycyrrhizae Radix et Rhizoma and its active components are being tried to treat various skin diseases, such as anaphylactoid purpura, psoriasis, eczema, pityriasis rosea, urticaria, systemic lupus erythematosus, eruption like papular acrodermatitis of childhood, herpes zoster, verruca plana, alopecia areata, leucoderma, skin pigmentation, etc. Research advances on the dermatopharmacology and clinic application of Glycyrrhizae Radix et Rhizoma as well as its flavonoids and glycyrrhizic acid in allergic dermatosis, tumor of skin, viral dermatosis, pigmentation, etc. are reviewed in this paper.

关 键 词：甘草 甘草黄酮类 甘草酸 变应性皮肤病 病毒性皮肤病 毛发生成 黑素生成 

分 类 号：R282.710.5[医药卫生—中药学]