黄体酮应用于早期先兆流产202例治疗效果分析  

Effect analysis of progesterone in treatment of threatened abortion 202 cases

作　　者：王珊 王玉东[2] 李刚 王继红 

机构地区：[1]开封市妇产医院妇二科,河南开封475000 [2]河南大学医学院

出　　处：《医药论坛杂志》2013年第3期47-48,共2页Journal of Medical Forum

摘　　要：目的验证黄体酮治疗早期先兆流产的有效性及安全性。方法将妊娠7～12周有先兆流产症状之孕妇随机分为研究组和对照组,研究组均给予黄体酮针20 mg肌肉注射,1次/d,待阴道出血减少或停止后,改为隔日注射黄体酮20 mg维持2周,再给予黄体酮20 mg1周2次,治疗1周作为巩固;对照组采用卧床休息、禁止性生活、口服维生素E和叶酸、中药保胎及止血对症治疗。观察腹痛和出血量。结果研究组的保胎成功率为68.3%,对照组为54.5%,两组比较,差异有统计学意义(P<0.05)。结论黄体功能不全所致早期流产常规予补充孕激素是安全、有效的。Objective To verify the efficacy and safety of progesterone in treatment of threatened abortion. Methods The pregnant women of threatened abortion when they were pregnancy for 7 ~ 10 weeks were randomly divided into stud- y group and control group. The study group was given progesterone, by intramuscular injecting progesterone 20 mg once a day, after vaginal bleeding reduce or stop, intramuscular injecting progesterone 20 mg once the next day and a total of 14 days. Then the study group was given progesterone twice one week. The control group was given the other methods to symptomatic treatment. Abdominal pain and bleeding were observed. Results The tocolysis success rate of the study group and control group were 681 3% and 54. 5% respectively and there was statistical significance. Conclusions U- sing progesterone in treatment of threatened abortion is safe and effective.

关 键 词：黄体酮 先兆流产 早期妊娠 

分 类 号：R984[医药卫生—药品]