南京地区患儿急性呼吸道感染常见病毒监测  

Etiological analysis of children with acute respiratory infection in Nanjing

作　　者：蒋旻[1] 赵艳丰[1] 张益红[1] 张永泉[1] 唐汝新[1] 王京雯[1] 司进[1] 

机构地区：[1]南京医科大学第二附属医院检验科,南京210007

出　　处：《中国卫生检验杂志》2013年第4期932-934,936,共4页Chinese Journal of Health Laboratory Technology

基　　金：南京医科大学科技发展基金重点项目(09NJMUZ19)

摘　　要：目的:分析南京地区儿童急性呼吸道感染病毒病原学检查结果,了解呼吸道病毒流行情况,为临床病毒病原学诊断、治疗提供依据。方法:取7459例急性呼吸道感染儿童鼻咽分泌物,采用直接免疫荧光法检测7种常见呼吸道病毒抗原。结果:我院三年中有3745份标本病毒检测阳性,主要是呼吸道合胞病毒(RSV)2305例,副流感病毒3型(PIV3)511例;病毒检出率在婴儿组和幼儿组较高,分别为55.82%和50.98%;冬季病毒检出率最高为69.26%;所致疾病以支气管肺炎最为多见。结论:2009年-2011年南京地区急性呼吸道感染的病毒仍以RSV为主要病原体,婴儿病毒感染率较高,儿童呼吸道病毒感染好发于冬季。Objective：To study the viral etiology detection of acute respiratory infection（ARI）in children of Nanjing in three years,so as to understand the virus prevalence and provide basis for viral etiology diagnosis and treatment.Methods： The nasopharyngeal aspirate samples were obtained from 7459 hospitalized children with ARI.Seven common respiratory viruses,including respiratory syncytial virus（RSV）,influenza virus A and B,parainfluenza viruses 1,2 and 3 and adenovirus were detected using direct immunofluorescence.Results： Virus were identified in 3745 cases,and RSV was the most common respiratory virus causing infection 2305 cases,followed by parainfluenza 3（PIV3） 511 cases.The infants at ages less than 1 year old and 1-3 years old had higher detection rate of viruses（55.82% and 50.98%,respectively）.The highest detection rate of viruses was found in winter and bronchopneumonia was the most frequent disease.Conclusion： RSV is the leading pathogen of ARI in children in Nanjing between Jan 2009 and Dec 2011.The children at age less than 3 years are susceptible to respiroviruses.The viral activity peaks in winter.

关 键 词：呼吸道感染 病毒 直接免疫荧光 儿童 

分 类 号：R373.1[医药卫生—病原生物学]