原发性肝癌患者癌症相关性乏力症状临床研究  

Clinical study on cancer-related fatigue symptom in patients with primary liver cancer

作　　者：陈坚[1] 李婷英[1] 魏燕[1] 吴俊兰[1] 

机构地区：[1]武警上海总队医院肿瘤科,上海201103

出　　处：《现代医药卫生》2013年第8期1140-1141,共2页Journal of Modern Medicine & Health

摘　　要：目的探讨原发性肝癌患者癌症相关性乏力症状与临床病理特征的关系。方法回顾性分析421例Ⅱ-Ⅳ期原发性肝癌患者的临床资料,并依据Chalder乏力评价量表判断乏力程度,分析乏力程度与临床病理参数的相关性。结果 421例Ⅱ-Ⅳ期原发性肝癌患者中有340例发生不同程度乏力,发生率为80.76%。乏力发生情况与年龄、Child-Pugh分级、病程、白细胞计数、血红蛋白量有关(P<0.05),但与性别、肿瘤分期、近期治疗方式无关(P>0.05)。结论原发性肝癌患者癌症相关性乏力症状与年龄、肝功能、病程、白细胞计数、血红蛋白含量有关。Objective To discuss cancer related fatigue in the patients with primary hepatocellular carcinoma and its relation with the clinicopathological features. Methods The clinical data in 421 cases of stage Ⅱ -Ⅳprimary liver cancer were performed the retrospective analysis ,the fatigue degree was evaluated by the Chalder fatigue assessment scale and its correlation with the clinicopathology parameters was analyzed. Results Among 421 cases of stage Ⅱ -Ⅳ primary hepatic carcinoma, 340 cases appeared weak in varying degrees, with the incidence rate of 80.76%. The fatigue occurrence was correlated with age,liver function, Child-Pugh grading ,course length ,WBC count and hemoglobin level （P〈0.05）,but not correlated with gender,tumor stage and recent treatment method （P〉0.05）. Conclusion Primary liver cancer related fatigue is correlated with age,liver function, disease course,WBC count and hemoglobin level.

关 键 词：肝肿瘤 病理学 疲劳 病因学 疲劳 病理学 癌症相关性乏力 

分 类 号：R512.62[医药卫生—内科学]