Xylyl derived oxacalixcrowns:Synthesis and crystal structure  

作　　者：Xiao-Yan Li Chun Hu Ming-Liang Ma Yahu A.Liu Xian-Qiang Mi Biao Jiang Ke Wen 

机构地区：[1]Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development,East China Normal University [2]Medicinal Chemistry,ChemBridge Research Laboratories Inc. [3]Sustainable Technology Research Center,Shanghai Advanced Research Institute,Chinese Academy of Science

出　　处：《Chinese Chemical Letters》2013年第4期279-282,共4页中国化学快报（英文版）

基　　金：Financial support from the National Natural Science Foundation of China(Nos.21071053,21002031,61078071);Shanghai Commission for Science and Technology(Nos.10ZR1409700, 09ZR1422500);"Strategic Priority Research Program"of Chinese Academy of Sciences(No.XDA01020304)are acknowledged

摘　　要：Oxacalixcrowns 1, 2 and 3 were synthesized via reactions of dihydroxyoxacalix[2]arene[2]pyrazine S with ortho-, meta- and para-bis（bromomethyl）benzenes in a 1：1 fashion. The structures and conformations of 1, 2 and 3 were established by a combination of NMR, mass spectroscopies and single crystal X-ray diffraction analysis.Oxacalixcrowns 1, 2 and 3 were synthesized via reactions of dihydroxyoxacalix[2]arene[2]pyrazine S with ortho-, meta- and para-bis（bromomethyl）benzenes in a 1：1 fashion. The structures and conformations of 1, 2 and 3 were established by a combination of NMR, mass spectroscopies and single crystal X-ray diffraction analysis.

关 键 词：areneOxacalixcrownCrown etherMacrocycle 

分 类 号：O621.3[理学—有机化学]