复方莪术油栓中呋喃二烯及莪术醇的测定  

Determination of Furanodiene and Curcumol in Compound Zedoary Turmeric Oil Suppositories

作　　者：牛冲[1] 张冬梅[1] 刘明洁[1] 

机构地区：[1]山东省食品药品检验所,济南250101

出　　处：《中国药品标准》2013年第2期131-133,共3页Drug Standards of China

摘　　要：目的:建立复方莪术油栓中呋喃二烯和莪术醇的含量测定方法。方法:采用《中国药典》2010年版复方莪术油栓〔含量测定〕项下色谱条件。结果:呋喃二烯在85.89～2579.4 ng范围内,莪术醇在16.272～488.16 ng范围内,线性关系良好,平均回收率分别为99%和97%,RSD分别为3.9%与4.0%(n=9)。结论:药典标准色谱条件可同时控制呋喃二烯和莪术醇的含量,为进一步完善复方莪术油栓质量标准提供了参考依据。Objective： To establish a new method for determination of furanodiene and curcumol in Compound Zedoary Turmeric Oil Suppositories. Method： The determination method of Compound Zedoary Turmeric Oil Suppositories in Ch. P. （edition 2010 ） was a- dopted. Results： The linearity were found in the range of 85.89-2579. 4 ng and 16. 272-488. 16 ng for furanodiene and curcumol re- spectively. The corresponding average recovery were 99% and 97% with RSD 3.9% and 4. 0% （n = 9）. Conclusion： The determi- nation method of Compound Zedoary Turmeric Oil Suppositories in Ch. P. edition 2010 can also determine the contents of furanodiene and curcumol. Thus the method was further improved.

关 键 词：复方莪术油栓 高效液相色谱法 呋喃二烯 莪术醇 

分 类 号：R921.2[医药卫生—药学]