高碳酸血症对中枢神经系统的作用  

Effect of Hypercapnia on Central Nervous System

作　　者：刘翔[1] 杨万超[1] 周曼 张兵 李文志[1] 

机构地区：[1]哈尔滨医科大学附属第二医院麻醉科 [2]黑龙江省麻醉与危重病研究重点实验室,黑龙江哈尔滨150086 [3]黑龙江省高校麻醉基础理论与应用研究重点实验室,黑龙江哈尔滨150086

出　　处：《现代生物医学进展》2013年第11期2197-2200,共4页Progress in Modern Biomedicine

基　　金：国家自然科学基金项目(81171076)

摘　　要：随着小潮气量通气策略和允许性高碳酸血症在急性呼吸窘迫征、急性肺损伤、肺部感染和其他肺部疾病中的推广和应用,高碳酸血症的肺脏保护作用及其机制也逐渐被阐明。研究表明,高碳酸血症对心血管、肝脏、胃肠道、脑等器官功能均有保护作用,尤其是其对中枢神经系统的影响已成为学者们关注的焦点问题。本文旨在总结高碳酸血症对中枢神经系统的作用。With the application of low-tide volume ventilatory strategy and permissive hypercapnia strategy in ALI or ARDS patients, the protective effect of hypercapnia on lungs and its mechanism are gradually recognized. Although the effects of hypercapnia on other organs of the body, such as cardiovascular system, liver and gastrointestinal tract, have been reported to be protective recently, the effect of hypercapnia on central nervous system is still a controversial issue. This paper was aimed to summarize the effect of hypercapnia on central nervous system.

关 键 词：高碳酸血症 中枢神经系统 脑保护 

分 类 号：R614.1[医药卫生—麻醉学]