无乳链球菌在非孕妇成人患者中的临床分布特点与耐药性分析  

Analysis on the distribution and drug sensitivities of streptococcus agalactiae in nonpregnant adults

作　　者：王艳艳[1] 任静[1] 徐燕[1] 陈雨华[1] 

机构地区：[1]江苏省无锡市人民医院检验科,江苏无锡214000

出　　处：《中国医药科学》2013年第7期87-88,共2页China Medicine And Pharmacy

摘　　要：目的了解本院无乳链球菌(GBS)在非孕妇成人患者中感染的临床分布特点和耐药情况,为临床感染的预防及治疗提供依据。方法收集本院非孕妇成人患者各类临床标本作无乳链球菌培养,经法国生物梅里埃VITEK-2全自动细菌鉴定分析仪进行鉴定和药敏分析。结果共分离出无乳链球菌102株,主要来源于阴道分泌物(23株)、尿液(43株)、痰液(32株)、脓液(2株)和创面(1株)。≥65岁患者有66例,占64.7%。102株无乳链球菌经药敏分析显示其对万古霉素、青霉素、利奈唑胺、头孢曲松和头孢丙烯均敏感,没有发现耐药株;红霉素、克林霉素和左氧氟沙星耐药性分别为49%、34.4%和12.8%。结论本院从非孕妇成年患者分离出的无乳链球菌主要引起生殖泌尿道感染和呼吸道感染,也会引起皮肤软组织感染和其他感染,主要分布于老年人和具有严重潜在疾病的人群。无乳链球菌感染非孕妇成人的病例不断增加,应引起广大医务工作者的关注。Objective To study the drug sensitivity and distribution of 102 clinical isolates of Streptococcus agalactiae and provide clinical guidance for treatment. Methods 102 clinical isolates of Streptococcus agalactiae were identified and their drug sensitivities were determined by automatic VITEK-2 system. Results 102 isolates were collected from July 2009 to September 2011, from vaginal secretions （23 isolates）, urine （43 isolates） and saliva（32 isolates）. All isolates were sensitive to Vancomycin , Penicillin, ceftriaxone, cefprozil and linezolid.The rate of patients above 65 ages is 64.7%（66 isolates）. The rate of drug resistance of the isolated Streptococcus agalactiae to erythromycin, clindamycin and levofloxacin was 49%, 34.4% and 12.8%, respectively. Conclusion Streptococcus agalactiae in non-pregnant adults primary cause genitourinary tract infections, respiratory infections, Skin and soft tissue infections and others. Resistances of Streptococcus agalactiae are not very serious, there are still a number of effective antibiotics.

关 键 词：无乳链球菌 临床分布 药物敏感性试验 

分 类 号：R195[医药卫生—卫生统计学]