低体重婴儿动脉导管未闭介入治疗研究  

Transcatheter occlusion of patent ductus arteriosus in small weight infants

作　　者：肖云彬[1] 黄希勇[1] 陈智[1] 王祥[1] 王勋[1] 

机构地区：[1]湖南省儿童医院心血管内科,长沙410007

出　　处：《介入放射学杂志》2013年第5期369-371,共3页Journal of Interventional Radiology

摘　　要：目的评价国产封堵器治疗动脉导管未闭(patent ductus arteriosus,PDA)低体重婴儿的有效性和安全性。方法 2010年10月至2011年10月应用国产封堵器治疗30例体重低于8 kg的PDA婴儿。术后24 h查血常规、尿常规,并于术后24 h、1、3和6个月行心脏彩色多普勒超声、胸部正位片、心电图检查。结果 1例患儿术后24 h彩色多普勒超声示残余分流,1个月随访时残余分流消失,其余29例术后及随访期间均未出现残余分流;未出现介入治疗的主要并发症,无一例死亡。结论应用国产PDA封堵器介入治疗体重低于8 kg的PDA婴儿的近、中期疗效确切,安全。Objective To evaluate the efficacy and safety of transcatheter occlusion of patent ductus arteriosus （PDA） by using domestic occluder in small weight infants. Methods During the period from Oct. 2010 to Oct. 2011 transcatheter occlusion of PDA by using domestic occluder was carried out in 30 PDA infants with body weight ≤ 8 kg. Two-dimensional and color Doppler echocardiography, chest radiograph, electrocardiogram, routine blood test and routine urine test were performed after the treatment in all infants. The results were analyzed. Results Colour Doppler echocardiography performed at 24 hours after the procedure showed that residual shunt was seen in one infant, which disappeared one month later. In the remaining 29 infants no residual shunt was detected during the follow-up period. Neither intervention-related complications nor death occurred. Conclusion For the treatment of PDA infants with body weight ≤8 kg, transcatheter occlusion of PDA by using domestic occluder is quite safe with reliable short-term and mid-term effieacv.（J Intervent Radiol. 2013. 22： 369-371）

关 键 词：动脉导管未闭 封堵器 低体重 婴儿 

分 类 号：R725.4[医药卫生—儿科]