经皮左房室瓣修复技术发展与现状  

Percutaneous mitral valve repair technique: its development and current situation

作　　者：郭倩倩[1] 陈笋[1] 

机构地区：[1]上海交通大学医学院附属新华医院儿心血管科,上海200082

出　　处：《介入放射学杂志》2013年第5期431-434,共4页Journal of Interventional Radiology

摘　　要：经皮左房室瓣修复是近年介入心脏病研究的新领域,由于其微创的特点已是左房室瓣修复术的首选方式。自1984年Inoue等完成首例经皮球囊左房室瓣成形术(PBMV)以来,PBMV术治疗左房室瓣狭窄在全球广泛开展,并取得了良好的短期及中远期临床效果。应用PBMV治疗左房室瓣狭窄患者时,左房室瓣瓣膜的解剖条件及年龄等都是患者良好预后的必要条件,也是选择病例时的参考因素。近年来左房室瓣关闭不全的介入治疗得到了快速发展,包括经左房室瓣边对边修补术和瓣环成形术。这些新技术仍处于初期阶段,虽初步证实其可行性,但是仍有许多问题需要进一步评估和改进。新技术的发展或许会成为高风险左房室瓣关闭不全患者的福音。Methods for percutaneous mitral valve repair have been widely studied in recent years. Percutaneous balloon mitral valvuloplasty （PBMV） was first performed by Inoue in 1984. Ever since then, the procedure for mitral stenosis has been widely used in the world. Satisfied short-term and mid-term results have been achieved. Pathologic changes of the mitral valve and the patient＇s age are the most important predictive factors, which should be taken into account when selection of patients for PBMV is made. In recent years, many interventional therapies for mitral regurgitation have been rapidly developed, including the mitral valve edge-to-edge suture procedure and prosthetic ring annuloplasty. These newly-developed percutaneous mitral valve repair techniques are still at their early stage, thus, further evaluation and pei：fection of these techniques are exceedingly needed before they can be safely and effectively employed in clinical practice. Potential percutaneous technique may be of great benefit to high-risk patients with mitral valve incompetence in the near future.（J Intervent Radiol, 2013, 22： 431-434）

关 键 词：经皮左房室瓣修复 左房室瓣狭窄 左房室瓣关闭不全 经皮左房室瓣球囊成形术 左房室瓣边对边修补术 瓣环成形术 

分 类 号：R654.2[医药卫生—外科学]