不同手术方式对POAG患者情绪及生存质量影响的比较  

Comparison of effects of different surgical methods on mentality and quality of life of patients with primary open-angle glaucoma

作　　者：谢瞻[1] 袁志兰[1] 

机构地区：[1]南京医科大学第一附属医院眼科,江苏省南京市210029

出　　处：《眼科新进展》2013年第5期453-456,共4页Recent Advances in Ophthalmology

摘　　要：目的比较不同手术方式对原发性开角型青光眼(primary open-angle glaucoma,POAG)患者情绪及生存质量产生的影响。方法收集POAG患者72例(72眼),其中接受小梁切除术(penetrating trabeculectomy surgery,PTS)患者36例,接受非穿透性小梁切除术(non-penetrating trabecularectomy surgery,NPTS)患者36例。所有患者术前采用家庭支持量表、Hamilton抑郁量表(HAMD)、Hamilton焦虑量表(HAMA)及低视力者生活质量量表(LVQOL)进行测试,术后3d采用HAMD、HAMA进行测试,术后1个月采用HAMD、HAMA及LVQOL进行测试。结果 PTS和NPTS组患者家庭支持量表总分、术前以及术后3d HAMA和HAMD总分差异均无统计学意义(均为P>0.05);术后1个月,PTS组患者HAMA总分高于NPTS组,差异有统计学意义(P=0.048)。术后3d两组患者HAMA总分、HAMD总分均较术前下降,差异均有统计学意义(均为P<0.05);术后1个月NPTS组患者HAMD总分较术后3d下降,差异有统计学意义(P=0.030),而PTS组患者HAMD总分与术后3d相似,差异无统计学意义(P=0.090)。术后1个月,PTS组患者LVQOL中远视力、移动、光感维度得分较术前降低,差异有统计学意义(P=0.002),调节维度得分较术前增高,差异有统计学意义(P=0.000),LVQOL总分及其余维度得分与术前相似,差异无统计学意义(均为P>0.05);NPTS组患者调节维度得分较术前增高,差异有统计学意义(P=0.000),LVQOL总分及其余维度得分与术前相似,差异均无统计学意义(均为P>0.05)。结论与PTS相比,NPTS治疗POAG术后患者情绪及生活质量有更明显的改善。Objective To investigate and compare the effects of penetrating trabecular surgery（PTS） and nonopenetrating trabecular surgery（NPTS） on mentality and quality of life in patients with primary open-angle glaucoma（POAG）. Methods Seventy-two cases （72 eyes） with POAG were equally divided into PTS group and NPTS group. All patients were tested with family support scale,Hamilton anxiety scale （HAMA）, Hamilton depression scale （HAMD） and low vision quality-of-life questionnair （LVQOL） preoperatively, with HAMA and HAMD at the 3 days postoperatively, with HAMA,HAMD and LVQOL 1 month after the operations. Results The total scores of family support scale, HAMA and HAMD preoperatively and at the 3 days postoperatively showed no significant difference between the two groups （ all P 〉 0.05 ）. The total score of HAMA of the PTS group was significantly higher than that of the NPTS group 1 month after the operation（P =0.048）. The total score of HAMD of the NPTS group 1 month after the operation was significantly lower than that at the 3 days postoperatively （P =0. 030）. while no significant difference was found between the total score of HAMD of the PTS group 1 month after the operation and that at the 3 days postoperatively（P = 0. 090）. One month after the operation, dimensionality of LVQOL（ farsightedness, mobility, light sensation） of the PTS group was significantly lower than that preoperatively （P = 0. 002）, no significant difference was found between the total score of LVQOL and the rest of dimensionality of LVQOL of the PTS group and those preoperatively, respectively （ all P 〉 0.05 ） ; Dimensionality of LVQOL （ modulation） of the NPTS group was significantly higher than that preoperatively （ P = 0. 000 ）, no significant difference was found between the total score of LVQOL and the rest of dimensionality of LVQOL of the NPTS group and those preoperatively, respectively（ all P 〉 0.05 ）. Conclusion NPTS can better improve mentality and quality of life

关 键 词：原发性开角型青光眼 非穿透性小梁切除术 焦虑 抑郁 生活质量 

分 类 号：R454.1[医药卫生—治疗学]