益气温阳方治疗慢性心力衰竭临床研究  

Clinical Study of Yiqi Wenyang Prescription in the Treatment of Chronic Heart Failure

作　　者：牟来品 周洪武 

机构地区：[1]通许县中医院,河南通许475400

出　　处：《中医学报》2013年第5期731-732,共2页Acta Chinese Medicine

基　　金：河南省科技攻关计划项目(编号:112102310317)

摘　　要：目的:观察益气温阳方治疗慢性心力衰竭的临床疗效。方法:将75例符合纳入标准的心肾阳虚证慢性心力衰竭患者按随机数字表单盲法分为治疗组38例和对照组37例。对照组给予常规西药治疗,治疗组在对照组的基础上加用益气温阳方(黄芪20 g,炮附子10 g,茯苓12 g,桂枝8 g,白术10 g,白芍10 g,丹参10 g,益母草15 g),两组疗程均为12周。于治疗前后观察6分钟步行距离(6MWT),行多普勒彩色超声心动图检测左室射血分数(LVEF)、左室舒张末期内径(LVEDD)、左室后壁厚度(LVPWD)。结果:治疗组有效率显著高于对照组(P<0.05);两组治疗前后LVEDD、LVPWD明显下降,治疗组与对照组比较,差异有统计学意义(P<0.05);两组治疗前后LVEF、6MWT均有明显升高,治疗组与对照组比较,差异有统计学意义(P<0.05)。结论:益气温阳法是治疗心肾阳虚证慢性心力衰竭的重要治法。Objective：To observe the clinical efficacy of Yiqi Wenyang prescription in the treatment of chronic heart failure. Methods：75 patients met the inclusion criteria of chronic heart failure with heart deficiency syndrome were randomly divided into treatment group（n = 38 ） and control group （ n = 37 ）. The control group was given conventional western medicine treatment. The treatment group was given ad- ditional Yiqi Wenyang prescription based on control group. Both the two groups took 12 weeks as one course of treatment. Observe 6MWT, left ventricular ejection fraction （LVEF） ,left ventricular end-diastolic dimension （LVEDD） and left ventricular posterior wall thickness （LVPWD） before and after treatment. Results：The effective rate in treatment group was significantly higher than that in control group （ P 〈 0.05 ）. The LVEDD and LVPWD in two groups were significantly decreased. Compared the two groups, the difference was statistically significant（P 〈 0.05 ）. The LVEF and 6MWT were significantly increased. Compared the two groups, the difference was significant（ P 〈 0. 05 ）. Conclusion ： Invigorating qi and warming yang treatment is important for chronic heart failure with heart deficiency syndrome.

关 键 词：慢性心力衰竭 心肾阳虚证 益气温阳 

分 类 号：R259.416[医药卫生—中西医结合]