长春西汀治疗早期糖尿病肾病的疗效观察  

Effect observation of vinpocetine on diabetic nephropathy at early stage

作　　者：罗宇家[1] 刘峰[2] 王艳军[2] 

机构地区：[1]中国医科大学,沈阳110001 [2]中国医科大学附属盛京医院内分泌科,沈阳110004

出　　处：《实用药物与临床》2013年第4期292-293,共2页Practical Pharmacy and Clinical Remedies

摘　　要：目的观察长春西汀对早期糖尿病肾病的治疗效果。方法选取在我院治疗的伴有早期糖尿病肾病的2型糖尿病患者(T2DM)40例,静脉注射长春西汀20 mg/d。给药前及给药15 d后检验尿微量白蛋白/尿肌酐、糖化血红蛋白及肝、肾功能等血清生化指标。结果治疗后40例T2DM患者的血肌酐无明显变化(P>0.05),尿微量白蛋白/尿肌酐显著降低(P<0.05)。结论长春西汀治疗早期糖尿病肾病具有较好的临床疗效。Objective To observe the curative effect of vinpocetine on diabetic nephropathy （DN） at early stage. Methods 40 type 2 diabetics mellitus patients complicated with DN were given vinpocetine by intravenous injection 20 mg/d. The levels of UMA/UCr, serum biochemistry, glycosylated hemoglobin and liver function index before and after 15 d of treatment were observed. Results After treatment, there was significant decrease in UMA/UCr （P 〈 0. 05 ） , but SCr didn＇t show the trend （P 〉 0. 05 ）. Conclusion Vinpocetine is effective to treat DN at early stage.

关 键 词：长春西汀 糖尿病 糖尿病肾病 

分 类 号：R587.2[医药卫生—内分泌]