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作 者:范愈燕[1] 和锡琳[2] 王向东[1] 朱燕波[3] 支楠[1] 张善冬[1] 曹飞飞[1] 贺飞[2] 张罗[1,2]
机构地区:[1]首都医科大学附属北京同仁医院,北京100730 [2]北京市耳鼻咽喉科研究所,北京100005 [3]北京中医药大学,北京100029
出 处:《世界中西医结合杂志》2013年第4期388-392,共5页World Journal of Integrated Traditional and Western Medicine
基 金:国家杰出青年科学基金(No.81025007);首都医科大学基础临床课题(No.11JL39)
摘 要:目的观察鼻鼽(变态反应性鼻炎及非变态反应性鼻炎)发病中医体质特点,探索中医体质因素在鼻鼽中的作用。方法汇集一年内就诊的15岁以上1008例"鼻鼽"患者,以致敏原的皮肤点刺试验及临床症状分为变态反应性鼻炎组(AR)和非变态反应性鼻炎组(NAR),分别对两组采用标准化中医体质量表(平和质、气虚质、阴虚质、阳虚质、痰湿质、气郁质、血瘀质、湿热质、特禀质)进行中医体质调查,再通过Logistic回归分析鼻鼽的中医体质特点。结果以1008例鼻鼽的患者中,相对平和质,阳虚质患NAR的概率增加,OR为2.78,95%CI为2.33~4.69;特禀质者患AR有显著增高,OR为3.84,95%CI为2.83~4.09,差异有统计学意义。气虚质者患AR及NAR的几率均等,两者均易发病。痰湿质、瘀血质、湿热质的危险度明显降低。结论阳虚质、气虚质是NAR发病的主要体质因素;特禀质、气虚质亦是AR发病的主要体质因素。Objective To observe the constitutional characteristics of traditional Chinese medicine in the pathogenesis of hiqiu( allergic rhinitis or non -allergic rhinitis)and explore the effect on biqiu in terms of constitutional factors of traditional Chinese medicine. Methods One thousand and eight cases of biqiu, o- ver 15 years old, visited in one year were collected. Based on the allergen skin prick test and clinical symp- toms, the cases were divided into an allergic rhinitis group ( AR group) and a non - allergic rhinitis group (NAR group). The standardized constitution in traditional Chinese medicine questionnaire (CCMQ) (harmo- nized constitution, qi deficiency constitution, yin deficiency constitution, yang deficiency constitution, phlegm damp constitution, qi stagnation constitution, blood stagnation constitution, damp heat constitution and special constitution) was adopted for the constitution investigation in two groups. Logistic regression was analyzed on the constitutional characteristics of traditional Chinese medicine. Results Of 1008 cases of biqiu, the possi- bility of yang deficiency constitution in NAR patients was increased corresponding to those of harmonized con- stitution, OR :2.78,95 %, C1:2.33 - 4.69 ;the possibility of special constitution in AR patients was increased significantly, OR : 3.84,95 % , CI : 2.83 - 4.09, indicating the statistically significant difference. The possibili- ty of qi deficiency constitution was equal between AR and NAR patients and both of AR and NAR were sus- ceptible. The risk for the patients of phlegm damp constitution, blood stagnation constitution and damp heat constitution was lower obviously. Conclusion Yang deficiency constitution and qi deficiency constitution are the main constitutional factors in the pathogenesis of NAR. The special constitution and qi deficiency constitu- tion are the main constitutional factors in the pathogenesis of AR.
关 键 词:变应性鼻炎 非变应性鼻炎 中医体质学 中医体质特点
分 类 号:R765.21[医药卫生—耳鼻咽喉科]
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