高校健康中青年教工颈动脉内膜中层厚度的测量及其评估意义  

The mean values of carotid intima-media thickness for different age groups in high school staff

作　　者：王晓红[1] 李建平[2] 

机构地区：[1]首都经济贸易大学校医院内科,北京100070 [2]北京大学第一医院心内科

出　　处：《中国综合临床》2013年第5期470-473,共4页Clinical Medicine of China

基　　金：“十一五”国家科技支撑计划项目（2003BA101A00）

摘　　要：目的通过较大规模群体调查了解不同年龄段人群颈动脉不同节段内膜中层厚度（IMT）平均值及其变化特点，为颈动脉超声健康评估提供依据。方法734名教职工按照性别和年龄分组，采用GELOGIQ7彩色超声仪对734名38～70岁健康职工双侧颈动脉IMT进行测量，每个受检者按照颈总动脉、窦部和颈内动脉三段分别取前后壁6个点测量IMT，取其均值为该段颈动脉IMT。38—40岁为1组，其余按照每5岁一个年龄段分组，获取各年龄段IMT均值数据。结果三段颈动脉IMT平均值随年龄增长逐渐增大，呈线性相关；不论男、女，颈内动脉IMT随年龄增长的幅度变化最小；窦部IMT大于颈总动脉IMT，颈内动脉IMT最薄。男、女同年龄段颈总动脉IMT均值相比46—50岁组，51—55岁组，56—60岁组差异均有统计学意义（P均〈0．05）；而男、女41—45岁组及61—65岁组比较差异均无统计学意义（P均〉0．05）；男性各组均值与年长5岁年龄组女性IMT均值相比差异均无统计学意义（P均〉0．05）。结论应用超声可准确测量颈动脉IMT，46～60岁年龄段中，男性比女性颈动脉IMT增厚约提早5年，且不同年龄段IMT均值，对人群的健康监测和心脑血管疾病预防有重要参考价值。Objective To investigate the mean values of carotid intima-media thickness （IMT） and change features according to gender, segments and age groups in general Chinese population, and provide the basis for the health assessment of carotid ultrasound. Methods GE LOGIQ 7 ultrasound scanner was used to measure IMT of 743 healthy cases aged from 38 to 70 years old. Six segments（ bilateral common carotid artery, bilateral carotid bulb, bilateral internal carotid artery） were measured for each case. All patients were divided into 6 age groups across 5 years to be one group. The mean values for each group was calculated. Results The average age of the three sections of carotid IMT gradually increasing linearly related; minimal change in men and women,the magnitude of the age of the internal carotid artery IMT;sinus IMT were greater than the common carotid artery IMT and carotid artery IMT thinnest, the mean carotid IMT of Men and women in the same age group, compared to the 46 -50 group, the group of 51 -55,56 -60 group, the differences were significant（ P 〈 0. 05） ;men and women 41-45 group and 61 - 65 difference between the groups was not statistically significant （P 〉 0. 05 ）;mean IMT difference of the male groups compared with the older group of women was not statistically significant （P 〉 0. 05）. Conclusion Ultrasound scanner can be used to measure IMT accurately. In the 46 - 60 group, carotid IMT thickening in men than women about 5 years earlier. The mean IMTs for different sex, age groups and segments would greatly benefit vascular health evaluation. It has a great significance in the prevention of cardiovascular and cerebrovascular diseases.

关 键 词：颈动脉 内中膜厚度 均值 年龄段 

分 类 号：R54[医药卫生—心血管疾病]