急性冠状动脉综合征围手术期中医证候与CRP关系研究  

Clinical Study of Relationship between TCM Syndrome and CRP during Perioperative Period of Acute Coronary Syndrome

作　　者：刘淑娟[1] 尹克春[1] 牛平平[1] 陈力[1] 周文斌[1] 

机构地区：[1]广东省中医院,广东广州510120

出　　处：《河南中医》2013年第5期700-702,共3页Henan Traditional Chinese Medicine

基　　金：广东省中医药管理局(编号:2009384)

摘　　要：目的:观察不同中医证型急性冠状动脉综合征(ACS)围手术期C反应蛋白(CRP)的变化,并探讨其临床意义。方法:选择ACS行介入治疗(PCI)患者80例,中医辨证分为本虚证、标实证、本虚标实证三组,用速率散射比浊法测定术前、术后血清CRP并进行比较。结果:①ACS术前中医证候以实证所占比例最大,其次分别为本虚标实证及本虚证,但随着年龄及病程的增加,虚证所占比例逐渐上升。②术前CRP水平测定,标实证>本虚标实证>本虚证,三组间有明显差异,有统计学意义;同组术前、术后比较,本虚标实证、本虚证两组介入术后CRP水平明显高于术前;标实证术后CRP较术前轻度升高,但无统计学意义(P>0.05)。结论:急性冠状动脉综合征介入治疗后更应注重扶正补虚、标本兼治,可能对减少围术期并发症、改善疾病预后有一定帮助。Objective： To observe the changes of C reactive protein （CRP） during perioperative period of acute coronary syndrome （ ACS ） of different TCM syndromes, and to explore its clinical significance. Methods ： 80 ACS patients treated with interventional therapy were divided into 3 groups according to TCM syndirome differentiation： root-deficiency syndrome, tip-excess syndrome, root-deficiency and tip-excess syndrome, preoperative and postoperative serum CRP levels were determined by rate nephelometry. Resuhs： （I） The excess syndromes before operation accounts for the largest proportion, followed by root-deficiency and tip-ex- cess syndrome and excess and deficiency, root-deficiency syndrome, but with the increase of age and course of disease, the pro- portion of deficiency syndrome gradually increased. （2） The determination of preoperative CRP levels fotlowed the orders ： tip-ex- cess syndrome, ruot-deficiency and tip-excess syndrome, root-deficiency syndrome, there are obvious differences between the three groups, with a statistical significance; The preoperative and postoperative comparison in the same group indicated flint CRP levels in the group of root-deficiency and tip-excess syndrome, and gcoup of root-deficiency syndrome after intervention therapy were significantly higher than those after the operation ; CRP levels in the group of tip-excess syndrome after intervention therapy increased slightly compared with those before the operation, but without statistical significance （ P 〉 0. 05 ）. Conclusion ： Strengthening the healthy qi and tonifying the deficiency should be stressed after the interventional treatment of ACS, which may be some help to reducing perioperative complications, and improving the prognosis of the disease.

关 键 词：急性冠状动脉综合征 C反应蛋白 冠状动脉介入治疗术 中医证候 

分 类 号：R541.4[医药卫生—心血管疾病]