急性高原病的病理生理表现及机制研究进展  

Research Progress in Mechanisms and Pathophysiology of Acute Mountain Sickness

作　　者：李琳[1,2] 马慧萍[1] 贾正平[1,2] 

机构地区：[1]兰州军区兰州总医院药剂科,全军高原环境损伤防治重点实验室,兰州730050 [2]兰州大学药学院,兰州730000

出　　处：《医学综述》2013年第8期1352-1354,共3页Medical Recapitulate

基　　金：国家科技部重大专项(2008ZXJ09004-52)

摘　　要：急性高原病(AMS)是人快速进入2500 m以上高原、暴露于低氧环境后产生的具有一系列病理生理学变化、功能紊乱及相应的各种临床症状的疾病。随着高原地区经济建设的迅速发展,进入高原的人逐年增多,高原病的发病率也逐渐增高,已成为制约高原经济发展和影响驻地军民身体健康的主要因素。研究AMS病理生理表现及其发病机制,对积极有效地预防和治疗AMS有重要意义。Acute mountain sickness（AMS） is characterized by a series of pathophysiological changes, functional disorders and other related symptoms experienced by people who quickly enter high altitude of over 2500m and low oxygen pressure environment. With the economic development of high altitude regions, a growing number of people work or travel at high altitudes, causing a rise in the morbidity of AMS, which seri- ously limits recreation and people＇s health at high altitude. In conclusion, a deeper understanding on mecha- nisms of AMS has great significance, fnr lha zctiva ant] affacliva nrav^nlinn nntl lrgAlrrlPnl

关 键 词：急性高原病 缺氧 发病机制 

分 类 号：R594.3[医药卫生—内科学]