基于磁分离的高通量核酸检测工作站控制系统设计  

Control System of High-throughput Nucleic Acid Detection Workstations Based on Magnetic Separation

作　　者：万遂人[1] 程铅[1] 何农跃[1] 刘宾[2] 

机构地区：[1]东南大学生物科学与医学工程学院,南京210096 [2]南京医科大学基础医学院生物医学工程系,南京210029

出　　处：《科技导报》2013年第13期54-57,共4页Science & Technology Review

基　　金：国家自然科学基金项目(60927001);国家高技术研究发展计划(863计划)项目(2007AA022007);国家重大科学研究计划项目(2010CB933903);国家科技重大专项(2009ZX10004-311);江苏省科技支撑计划项目(BE2009147)

摘　　要：核酸检测工作站主要是由光、机、电等部分构成的高精度生化分析仪器,其功能模块主要有:高通量磁分离系统、微量移液系统、精确温控系统、荧光信号检测系统。根据以上系统应用要求,简要介绍了系统硬件框架。基于硬件基础,系统软件采用树形控件完成了实验流程设计;采用MFC绘图完成了美观、易操作的实验属性设置和工作台布局设置,采用多线程监控技术实现与下位机RSC-485串口通信;采用Access数据库保存实验流程及结果,并导出打印实验数据等。The nucleic acid detection workstation is a high-precision biochemical analytical instrument composed of optical, mechanical, electrical and other components. There are four functional modules in the workstation, including the high throughput magnetic separation system, the micro-volume pipetting system, the accurate temperature control system and the fluorescent signal detection system. According to the requirements of the above systems, a brief introduction is given for the framework of the hardware system. Based on the hardware functions, the software system completes the design of the experimental process using the tree control： an easy to use and good looking experimental property setting interface and a workbench layout with the MFC drawing. Serial communications are carried out through the slave PC＇s RSC-485 port with muhi-threaded monitoring technologies： saving the experimental processes and results, exporting experimental data with the access database programming for their printing.

关 键 词：核酸分析系统 磁分离 串口通信 数据库编程 

分 类 号：TP311.52[自动化与计算机技术—计算机软件与理论]