CRP在小儿急性上呼吸道感染诊断与治疗中的应用价值分析  

Clinical value of CRP in diagnosis and treatment with children's acute upper respiratory tract infection

作　　者：王有峰[1] 李洁冰[1] 王东丽[1] 

机构地区：[1]南阳市第一人民医院,河南南阳473000

出　　处：《基层医学论坛》2013年第10期1231-1233,共3页The Medical Forum

摘　　要：目的分析末梢血C反应蛋白(CRP)在小儿急性上呼吸道感染诊断及治疗中的应用价值。方法选择急诊首诊为急性上呼吸道感染的患儿494例作为研究对象,对患儿末梢血白细胞(WBC)、中性粒细胞(N)、CRP分布情况进行统计分析,观察CRP正常儿童应用抗菌药物治疗和非抗菌药物治疗的效果。结果494例患儿中,CRP<20 mg/L 390例,CRP>20 mg/L 104例。在CRP升高组中WBC平均值高于CRP正常组,2组间差异有统计学意义(P<0.01);CRP升高组血清CRP与WBC和N均呈正相关(r分别为0.439,0.554,P均<0.01)。在CRP正常的390例患者中,随机分为非抗生素治疗组和抗生素治疗组,进行5 d内疗效比较,差异无统计学意义(P>0.05)。结论末梢血CRP含量的检测有助于临床对小儿上呼吸道是否有细菌感染的早期诊断,对是否应用抗菌药物治疗具有重要的指导作用,可以减少抗菌药物的不合理使用。Objective research is to study the value of the peripheral blood c-reactive protein （CRP） in diagnosis and treatment of acute upper respiratory tract infection children. Methods A total of 494patients firstly diagnosed as upper respiratory tract from the emergency department were collected. The WBC, N and CRP in peripheral blood were deteeted. The relationship between antibiotics therapy and out comes was investigated. Results Of 494 cases, CRP level was not more than20mg/L, in 390 cases. And CRP〉50 mg/L inl04eases. The mean WBC in patients with CRP〉50 mg/L was higher than that inpatients withCRP20mg/L （P〈0.01）. There is a positive correlation among serum CRP, WBC and neutrophils percentage （N） in the 104 unhealthy children, and the statistical index r respectively show as 0.439 and 0.554, and the statistical significance index P is 0.01. he incidence of pyre-tolysis in5d had no difference between antibiotics treated patients and no antibiotics treated patients （P〉0.05）. Conclusion The peripheral CRP is valuable in the early diagnosis for if patients had already got the acute upper respiratory traet infection eansed by baeteria, and it has a important guiding role in the using of antibacterial drug therapy, and it can reduce the unreasonable using of antibaeterial drug.

关 键 词：小儿急性上呼吸道感染 CRP 抗生素 应用价值 

分 类 号：R725.6[医药卫生—儿科]