肠杆菌科细菌碳青霉烯耐药机制研究与感控策略  

Mechanisms of carbapenem resistance in Enterobacteriaceae and the strategies for control of carbapenem-resistant Enterobacteriaceae

作　　者：刘丁[1] 张莉萍[2] 

机构地区：[1]第三军医大学大坪医院感控中心,重庆400042 [2]重庆医科大学附属第一医院检验科

出　　处：《中华检验医学杂志》2013年第4期300-302,共3页Chinese Journal of Laboratory Medicine

摘　　要：国内外监测数据显示，碳青霉烯类抗生素耐药肠杆菌科细菌（CRE）不断增多，给临床抗感染治疗带来极大的挑战，已成为全球关注的焦点问题。高度关注临床微生物实验室的能力建设，积极开展肠杆菌科细菌碳青霉烯耐药机制研究，切实提高实验室对CRE的检测水平，加强抗菌药物临床合理应用的监管，严格执行手卫生和消毒隔离制度，是预防CRE院感发生的有效措施。（中华检验医学杂志．2013．36：300-302）、Monitoring data of antibiotic susceptibility from both home and abroad showed that earbapenem-resistant Enterobaeteriaeeae （CRE） are being on the rise, which represents an increasingly urgent clinical danger and an emerging public health concern worldwide. In order to effectively prevent CRE transmission in healtheare settings, we should not only pay high attention to the capability building of the laboratory of clinical microbiology, but also actively explore into the mechanisms of earbapenem resistance in Enterobacteriaceae. What＇s more, we should substantially raise the detection capacity of laboratory on CRE, effectively carry out the antimicrobial stewardship program, and strictly implement hand hygiene and contact precautions. （ Chin J Lab Med ,2013,36：300-302 ）

关 键 词：肠杆菌科 卡巴配能类 抗药性 细菌 感染控制 实验室 医院 

分 类 号：R378.2[医药卫生—病原生物学]