一次性运动对血液TLR-4及其诱导产物的影响  

Effects of Acute Exercise on the Expression of Blood TLR-4 and Its Induced Products

作　　者：邱天[1] 王馨塘[2] 张爱芳[2] 

机构地区：[1]龙岩学院,福建龙岩364012 [2]北京体育大学,北京100084

出　　处：《龙岩学院学报》2013年第2期74-77,91,共5页Journal of Longyan University

基　　金：教育部博士点新教师基金课题(20091112120004)

摘　　要：对10名非体育专业大学生进行60%VO2max的跑步机运动,在运动前1 h,运动后0、1、2、24 h抽取静脉血,测定血液中白细胞表面TLR-4 mRNA表达和血清TLR-4、NF-кB的蛋白水平。结果表明,60%VO2max运动后即刻的血液中白细胞表面TLR-4 mRNA表达和血清TLR-4蛋白水平下降,血清NF-кB上升;除了TLR-4 mRNA表达,其他指标都在24 h后恢复到运动前水平。The paper studies the effects of acute 60%VO2max exercise on Toll receptor 4 mRNA expression, the serum protein level and its induced products influence, discusses the relationship between exercise and immunity, provides a theoretical help to public health and some other sport fields. The results are as follows： Immediately after 60% VO2max exercise, blood mononuclear cell surface TLR-4 mRNA expression and TLR-4 serum protein levels decrease, serum NF -κB protein levels rises; Except TLR-4mRNA expression, other indicators return to the levels before exercise within 24 hours.

关 键 词：TOLL样受体4 免疫 运动 

分 类 号：Q599[生物学—生物化学]