CO_2激光与纤维蛋白粘合剂修复颅神经的比较  

Comparison of CO_2 laser and fibrinogen tissue adhesive on cranial nerve repair

作　　者：王彦刚[1] 章翔[1] 刘卫平[1] 段新民[2] 杨继庆[2] 

机构地区：[1]第四军医大学西京医院全军神经外科研究所,陕西西安710033 [2]第四军医大学生物医学工程系物理学教研室,陕西西安710033

出　　处：《第四军医大学学报》2000年第9期1147-1149,共3页Journal of the Fourth Military Medical University

摘　　要：目的　探讨激光吻合颅神经的可能性 .方法　家猫10只的两侧动眼神经在颅内段切断 ,分别以 CO2 (12 0 m W,光斑长 0 .2 cm,宽 0 .3mm)激光原位吻合或常规纤维蛋白粘合剂修复 ,术后进行瞳孔对光反射、神经纤维直径、通过率等指标的观察 .结果　 14wk后激光吻合组瞳孔对光反射功能优于纤维蛋白粘合剂组 ,激光组瞳孔直径为 2 .3mm,纤维蛋白粘合剂组为 3.1m m.神经组织学观察激光组轴突再生情况好 ,神经纤维通过率达 82 .0 % ,明显好于纤维蛋白粘合剂吻合组 71.0 % .结论　CO2AIM To study the feasibility of carbon dioxide laser on severed cranial nerves. METHODS The bilateral intracranial oculomotor nerve of cats were transected. Then one side was welded by linear mode carbon dioxide laser at the local site, and another side repaired by fibrinogen tissue adhesive. Reflextion of pupils, diameter of regenerationfibers and rate of fibers crossing anastomosis area were recorded and analysed postoperatively. RESULTS After 14 weeks, the pupil of the laser anastomosis side recovered from amplifying in denervation; the pupil diameter was 2.3 mm, the fibrinogen tissue adhesive sides was 3.1 mm. Histomorphological examinations revealed good axon regeneration. The rate of nerve fibers crossing laser anastomosis area was 82.0%; the fibrinogen tissue adhesive sides was 71.0%, and no remarkble damages were found. All these were superior to the fibinogen tissue adhesive group. CONCLUSION The carbon dioxide laser can be used effectively in the microsurgical repair of cranial nerves.

关 键 词：颅神经 纤维蛋白粘合剂 修复 CO2激光 

分 类 号：R651[医药卫生—外科学] R616.2[医药卫生—临床医学]