胰岛素强化治疗严重心衰合并肺部感染高血糖患者的疗效  

Clinical Efficacy of Intensive Insulin for the Treatment of Severe Heart Failure Patients with Lung Infection and Hyperglycemia

作　　者：李立艳[1] 杨瑞华[1] 黄亚薇[1] 

机构地区：[1]北京市朝阳区第二医院内科,北京100026

出　　处：《医学临床研究》2013年第4期735-736,共2页Journal of Clinical Research

摘　　要：【目的】观察胰岛素强化治疗严重心衰合并肺部感染高血糖患者的疗效。【方法】本院80例严重心衰合并肺部感染高血糖患者随机分为两组，A组42例，给予胰岛素强化治疗，使血糖控制在4．4～7．8mmol／L；B组38例，给予常规胰岛素治疗，使血糖控制在10～11．1mmol／L。观察两组抗生素使用时间，住院时间，并发症发生率，病死率，住院总费用等情况。【结果】A组患者抗生素使用时间，住院时间短于B组，并发症发生率，病死率，住院总费用明显低于B组，并且由于密切观察血糖而无低血糖的发生。【结论】严格控制血糖可明显的改善严重心衰合并肺部感染高血糖患者的预后，节约费用，避免严重的低血糖发生。[Objective]To observe the efficacy of intensive insulin for the treatment in severe heart failure pa- tients with lung infection and hyperglycemia. [Methods]Eighty severe heart failure patients with lung infection and hyperglycemia in our hospital were divided into two groups. Group A（ n =42） was given intensive insulin therapy with blood glucose 4.4~7.8mmol/L. Group B（ n --38） was given routine insulin therapy with blood glucose 10~ 11.1 mmol/L. Duration of antibiotic usage, hospitalization day, the incidence of complications, mortality and total cost of hospitalization in patients of two groups were observed. [Results]The duration of antibiotics usage and hospitalization time in group A were shorter than those in group 13, and the incidence of complications, mortality and hospitalization expenses in group A were obviously lower than those in group B. No hypoglycemia occurred due to careful observation. [Conclusion]Strictly controlling blood glucose can obviously improve the prognosis of severe heart failure patients with lung infection and hyperglycemia, and decrease the hospitalization expenses, and avoid the incidence of severe hypoglycemia.

关 键 词：心力衰竭 并发症 肺炎 并发症 高血糖症 药物疗法 胰岛素 投药和剂量 

分 类 号：R541.61[医药卫生—心血管疾病]