老年慢性阻塞性肺疾病或冠心病合并肺栓塞患者血浆脑钠肽、D-二聚体、C反应蛋白及心肌酶的变化  

Serum brain natriuretic peptide,D-dimer C-reactive protein and myocardial enzymes levels in elderly patients of chronic obstructive pulmonary disease or coronary heart disease complicated with pulmonary embolism

作　　者：唐婷玉[1] 陆晓玲[1] 吴健[1] 钦光跃[1] 

机构地区：[1]浙江医院呼吸科,杭州310013

出　　处：《浙江医学》2013年第8期637-638,652,共3页Zhejiang Medical Journal

基　　金：浙江省中医药科学研究基金项目(2012ZA009)

摘　　要：目的探讨血浆脑钠肽(BNP)、D-二聚体(D-D)、血清C反应蛋白(CRP)、心肌酶在老年慢性阻塞性肺疾病(COPD)或冠心病(CHD)合并肺血栓栓塞症(PE)患者的变化。方法测定老年COPD合并PE患者20例(COPD组)和老年CHD合并PE患者21例(CHD组)BNP、D-D及CRP、心肌酶水平,比较其差异。结果 COPD组与CHD组比较BNP、D-D、CRP、心肌酶差异均无统计学意义(P>0.05)。结论在诊断老年PE过程中,需提高诊断意识,以减少漏诊、误诊,降低病死率。Objective To investigate the changes of serum brain natriuretic peptide （BNP）, D-dimer （D-D）, C-reactive protein （CRP） and myocardial enzymes levels in elderly patients of chronic obstructive pulmonary disease （COPD） or coronary heart disease （CHD） complicated with pulmonary embolism （PE）. Methods The serum levels of BNP, D-D, CRP and myocardial enzymes were measured in 20 COPD patients complicated with PE （COPD group） and 22 CHD patients complicated with PE （CHD group）. Results There were no differences in serum levels of BNP, D-D, CRP and myocardial enzymes between COPD and CHD groups （P 〉0.05）. Conclusion There is no difference in diagnostic indicators for PE between elderly COPD patients and CHD patients.

关 键 词：老年 肺血栓栓塞症 血浆脑钠肽 D-二聚体 C反应蛋白 心肌酶 

分 类 号：R563.9[医药卫生—呼吸系统] R541.4[医药卫生—内科学] R563.5[医药卫生—临床医学]