Synthesis and Bioactivities of Novel N-（4-（2-Aryloxythiazol- 5-yl）but-3-yn-2-yl）benzamides  

作　　者：Youquan Zhu Pei Liu Danyang Wang Jin Zhang Jie Cheng Yuan Ma Xiaomao Zou Huazheng Yang 

机构地区：[1]State Key Laboratory of Elemento-organic Chemistry, Institute of Elemento-organic Chemistry, Nankai University, Tianjin 300071, China

出　　处：《Chinese Journal of Chemistry》2013年第2期173-181,共9页中国化学（英文版）

基　　金：We are grateful for financial support by the National Basic Research Program of China (973 Program)，the National Natural Science Foundation of China，the National Key Technologies R&D Program

摘　　要：A series of novel N-（4-（2-aryloxythiazol-5-yl）but-3-yn-2-yl）benzamide derivatives were designed and synthesized. Their structures were identified by IH NMR and elemental analyses. Preliminary bioassays indicated that some title compounds provided 〉 80% control of Selerotinia selerotiorum at 50 μg/mL and 〉 70% herbicidal activities against B. campestris at 100 μg/mL. Their structure-activities relationships were also discussed.A series of novel N-（4-（2-aryloxythiazol-5-yl）but-3-yn-2-yl）benzamide derivatives were designed and synthesized. Their structures were identified by IH NMR and elemental analyses. Preliminary bioassays indicated that some title compounds provided 〉 80% control of Selerotinia selerotiorum at 50 μg/mL and 〉 70% herbicidal activities against B. campestris at 100 μg/mL. Their structure-activities relationships were also discussed.

关 键 词：fungicides BENZAMIDE ACCASE aryloxythiazole herbicide 

分 类 号：TQ464.71[化学工程—制药化工] O621[理学—有机化学]