Rare-Earth Metal Chlorides Catalyzed One-pot Syntheses of Quinolines under Solvent-free Microwave Irradiation Conditions  

作　　者：Lijun Zhang Bing Wu Yongqing Zhou Jing Xia Shuangliu Zhou Shaowu Wang 

机构地区：[1]Laboratory of Functionalized Molecular Solids, Ministry of Education, Anhui Laboratory of Molecule-Based Materials, Institute of Organic Chemistry, College of Chemistry and Materials Science, Anhui Normal University, Wuhu, Anhui 241000, China [2]State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Shanghai 200032, China

出　　处：《Chinese Journal of Chemistry》2013年第4期465-471,共7页中国化学（英文版）

基　　金：The work was supported by the National Natural Science Foundation of China （21172004, 21172003 and 21072004）, the National Basic Research Program of China （2012CB821604）, and grants from the Ministry of Education （20103424110001）.

摘　　要：Under microwave irradiation and solvent-free conditions, rare-earth metal chlorides （RECl3） have been efficient catalysts for one-pot synthesis of quinoline derivatives to give products in good to excellent yields through the mul- ti-component reactions of aldehydes, amines, and alkynes. The rare-earth metal chlorides can be recycled for six times without notable loss of catalytic activities. This new synthetic approach has prominent features of a short re- action time, high yields of products, operational simplicity, broad substrate scopes, environmentally friendly prop- erty and commercially available catalysts. It extends the applications of rare-earth metal compounds as catalysts in organic synthesis.Under microwave irradiation and solvent-free conditions, rare-earth metal chlorides （RECl3） have been efficient catalysts for one-pot synthesis of quinoline derivatives to give products in good to excellent yields through the mul- ti-component reactions of aldehydes, amines, and alkynes. The rare-earth metal chlorides can be recycled for six times without notable loss of catalytic activities. This new synthetic approach has prominent features of a short re- action time, high yields of products, operational simplicity, broad substrate scopes, environmentally friendly prop- erty and commercially available catalysts. It extends the applications of rare-earth metal compounds as catalysts in organic synthesis.

关 键 词：rare earth QUINOLINE multi-component reaction microwave irradiation RECYCLABLE 

分 类 号：O614.33[理学—无机化学] TQ325.14[理学—化学]