高压氧对高原脱习服过程中红细胞指标的影响  

Effects of Hyperbaric Oxygen on Red Blood Cell Index of Human De-adaptation to High Altitude

作　　者：崔建华 高亮 王福领 王琰 马广全 李彬 

机构地区：[1]解放军第十八医院,44900

出　　处：《高原医学杂志》2012年第4期8-10,共3页Journal of High Altitude Medicine

基　　金：高原医学教育部重点实验室资助项目(2011JSGY05);军队"十一五"攻关项目(08G081)

摘　　要：目的:探讨高压氧(HBO)治疗对高原脱习服症者红细胞指标的影响。方法:对驻守海拔5 000m以上地区1年的20名男性青年,在返回平原(海拔1 400m)第2天开始进行HBO治疗,连续治疗10天。在治疗前、治疗第7天和第10天清晨分别采空腹静脉血检测血红蛋白(Hb)及红细胞指标。结果:治疗第7天较治疗前,红细胞计数(RBC)、红细胞压积(Hct)、红细胞平均血红蛋白含量(MCH)、平均红细胞血红蛋白浓度(MCHC)降低,有非常显著性差异(P<0.01),Hb、平均红细胞体积(MCV)无统计学差异(P>0.05);治疗第10天较治疗前,RBC、Hct、MCH、MCHC、Hb降低,有显著性差异(P<0.01或<0.05),MCV无统计学差异(P>0.05)。治疗第10天较治疗第7天,Hct降低,有显著性差异(P<0.05),其余无统计学差异(P>0.05)。结论:HBO可使高原脱习服症者红细胞数减少,降低红细胞黏度,增强红细胞变形能力,促进血液循环和新陈代谢。Objective：To explore the effects of hyperbaric oxygen on red blood cell index of human de-adaptation to high altitude.Methods：20 young men,who have lived above 5 000m altitude for 1 year,were acutely exposed to 1 400m lowland.Then they were treated with hyperbaric oxygen on the 2nd postlowland for 10 days.The level of Hb,Hct,MCH and MCHC were detected before and 7d and 10d after treatment.Results：As compared with pre-treatment,level of RBC,Hct,MCH and MCHC reduced significantly（P＆lt;0.01） after 7d treatment,but no difference for Hb and MCV（P＆gt;0.05）;and level of RBC,Hct,MCH,MCHC,HGB reduced significantly（P＆lt;0.01 or ＆lt;0.05） after 10d treatment,no difference in MCV（P＆gt;0.05）.a Level of Hct reduced significantly after 10d treatment compared with 7d treatment（P＆lt;0.05）.Conclusions：Treatment of hyperbaric oxygen can reduce number of RBC and depress it’s viscosity and boost up anamorphic ability and thus to accelerate blood circulation and metabolism,and to improve micro-circle and hemorheology of human de-adaptation to high altitude.

关 键 词：高原脱习服症 HBO 治疗 红细胞 

分 类 号：R594.3[医药卫生—内科学]