脓毒症血钙水平与预后的关系  

Serum level of calcium in sepsis patients is associated with severity of disease and deteriorating prognosis

作　　者：姜远普[1,2] 张川[1,2] 郑碧霞[1,2] 

机构地区：[1]重庆医科大学成都第二临床医学院 [2]成都市第三人民医院重症监护室,四川成都610031

出　　处：《西部医学》2013年第2期249-250,253,共3页Medical Journal of West China

摘　　要：目的探讨血钙与脓毒症患者严重程度及预后的关系。方法对收治的108例脓毒症患者,根据血钙值分为3组,比较3组APACHEⅡ评分、多器官功能障碍综合征(MODS)发生率及病死率。同时对108例脓毒症患者根据是否存活分为存活组及死亡组,比较两组血钙值、年龄、白细胞(WBC)数。结果 3组APACHEⅡ评分、MODS发生率及病死率比较差异有统计学意义(P<0.05);死亡组血钙值明显低于存活组(P<0.01),而存活组与死亡组年龄、白细胞数比较差异无统计学意义(P>0.05)。结论脓毒症患者血钙越低,病情越重,预后越差。血钙水平和APACHEⅡ评分一样,可作为评价脓毒症患者疾病严重程度及预后一个较可靠指标。Objective To study the relationship of calcium level with the severity of sepsis and patients＇ outcome. Methods 108 patients with sepsis were included in this study. They were divided into three groups according to the serum level of calcium. APACHE II scores, morbidity of multiple organ dysfunction syndrome （MODS） and mortality were compared among these three groups. Meanwhile, these subjects were also divided into survive group and death group according to their outcome. Compared serum level of calcium, age, and white blood cell （WBC） count in the two groups. Results There were significant differences among these three groups for APACHE ; scores, morbidity of MODS and mortality （P〈0. 05）. Calcium level remarkably decreased in death group, as compared to that in survival group （P〈 0. 01）. However, we found no apparent differences for age and WBC count between the two groups （P〉0. 05）. Conclusion Serum calcium level was significantly lower in patients with more severe sepsis and higher mortality. Serum calcium level, as APACHE H scores, could be an effective predictor of severity of sepsis and prognosis.

关 键 词：血钙 脓毒症 严重程度 预后 

分 类 号：R631.2[医药卫生—外科学]