临床药师干预Ⅰ类切口围手术期预防使用抗菌药物的效果分析  

Analysis of the effect of clinical pharmacists' intervention in surgical prevention use of antibiotics in type I incision

作　　者：杨思芸 李胜前[1,2] 曾友志 朱丽莎[1,2] 苏强 李林[1,2] 

机构地区：[1]南充市中心医院临床药学科 [2]川北医学院第二临床医学院,四川南充637000

出　　处：《西部医学》2013年第2期282-285,共4页Medical Journal of West China

基　　金：四川省卫生厅资助课题(110612)

摘　　要：目的对比评价临床药师对I类切口围手术期抗菌药物使用进行全程持续干预前后的效果。方法通过临床药师实施的一系列措施来改变临床围手术期抗菌药物不合理使用现状,从抗菌药物的适应证、品种选择、用药时机、用法用量等方面进行综合评价干预效果,并与干预前进行比较。结果经临床药师干预,医师对围术期患者预防用药在适应证、具体品种、用法用量、使用权限、溶媒选择、给药途径、联合用药、给药时机和禁忌症等方面较干预前均明显得到规范;人均住院药品总费用占总住院费用的比例由29.4%降至9.33%,人均抗菌药物总费用占总住院费用的比例由13.20%降至0.00%;人均总住院时间由12.3天降至6.3天;人均抗菌药物预防应用时间由5.2天降至0.16天。结论临床药师对围术期预防应用抗菌药物实施干预是切实可行的,可规范临床抗菌药物的应用。Objective To evaluated clinical pharmacists＇ intervening perioperative prophylactic applcation of antibiotics in surgical opera＇tion. Methods Through clinical pharmacists organized a series of measures to change the phenomenon of peroperative period irrational using of antibiotics. The intervention effect included the indications, choice of drugs, usage and dosage, super power application of antibacterial drugs, solvent selection, route of administration, drug combination, time administration and contraindication were valuationed and compared with the previous data to validate the intervention effect. Results Through intervention of clinical pharmacist, the perioperative prophylactic applactication of antibiotics was improved significantly in respect of indication, antibacterial selection, dosage and usage, drug use permissions, solvent selection, route of administration, drug combination, administration time and contraindication. The proportion of total drug cost in total hospitalization costs decreased from 29.44% to 9.33% % the percentage of total of antibiotics in total hospitalization costs decreased from 13.20% to 0.00% ;Total hospitalization day decreased from 12.3 days to 6.3days. Duration of antibiotic use decreased from 5.20 days to 0.16 days. Conclusion It was practicable and effective that clinical pharmacist intervene perioperative prophylactic application of antibiotics. Clinical pharmacists played an active role on promoting prophylactic application of antibiotics safely, rationally, effectively and economically in perioperative period.

关 键 词：临床药师 Ⅰ类切口 围手术期 抗菌药物 

分 类 号：R969.3[医药卫生—药理学]