Sysmex XE-2100检测恶性肿瘤并发贫血患者外周血有核红细胞及对白细胞结果的准确性评估  

Accuracy Evaluation of WBC Counting Function of Sysmex XE-2100 Hematology Analyzer in Malignant Tumor Anemic Patients with Nucleated Red Blood Cell in Peripheral Blood

作　　者：冯戟[1] 罗丹[1] 马红雨[1] 赵瑞敏[1] 刘晓莉[1] 王照峰[1] 李莹[1] 朱美财[1] 

机构地区：[1]北京空军总医院临床检验中心,北京100142

出　　处：《现代检验医学杂志》2013年第2期123-125,128,共4页Journal of Modern Laboratory Medicine

摘　　要：目的探讨Sysmex XE-2100全血细胞分析仪检测外周血出现有核红细胞的恶性肿瘤患者的白细胞结果的准确性。方法收集2011年12月-2012年12月血液、呼吸、消化、妇产、外科等系统恶性肿瘤并发贫血患者外周血共440例，采用Sysmex XE-2100全血细胞分析仪（未开NRBC模式）进行血液细胞分类计数检测，其中全血细胞分析仪报警NRBC并经过人工涂片镜检分类证实125例，分别采用全血细胞分析仪方法（NRBC模式）及人工涂片镜检分类方法和仪器计数白细胞相结合计数白细胞。结果不同系统恶性肿瘤并发贫血患者NRBC百分比不同，妇科肿瘤NRBC百分比为38．5％，泌尿系统肿瘤NRBC百分比为37．5％，血液系统肿瘤NRBC百分比为36．9％。全血细胞分析仪（NRBC模式）检测白细胞的中位数为3．56×10^9／L，与人工镜检分类计数检测白细胞3．56×10^9／L比较t=-1．852，P=0．066，差异无统计学意义。结论Sysmex XE-2100全血细胞分析仪具有检测NRBC的功能，对外周血出现有核红细胞恶性肿瘤贫血患者白细胞的准确计数有重要的临床意义。Objective To evaluate accuracy of WBC counting function of Sysmex XE-2100 hematology analyzer in malignant tumor anemic patients with nucleated red blood cell. Methods NRBC percentage of 440 different system malignant tumor combined with anemic patients selected from the departments of hematology, respiratory, gastroenterology, gynecology and surgery were detected from Dec. 2011 to Dec. 2012. Counting and classification of blood cells of patients were detected by XE-2100 hematology analyzer （without NRBC mode）. 125 blood samples of malignant tumor anemic patients with nucleated red blood cell （NRBC） hinted by the Sysmex XE-2100 hematology analyzer and confirmed by manual smear classification with microscopy simultaneously were selected. White blood cells of these blood samples were counted by hematology analyzer （with NRBC mode） method and manual method with microscopy. Results NRBC percentage of different system malignant tumor anemic patients were different. NRBC percentage of gynecologic Oncology was 38.5 % NRBC percentage of urinary system tumors was 37.50/00. NRBC percentage of blood system tumors was 36.9% 3.56 7× 10^9/L was the media of WBC counting by Sysmex XE-2100 hematology analyzer, and 3.56 × 10^9/L was the media of WBC counting by manual method. There were no significant difference between two methods（t= -1. 852,P=0. 066）. Conclusion NRBC detection fuction of Sysmex XE-2100 hematology analyzer is very important for clinical application significance in accuracy of WBC counting in malignant tumor anemic patients with nucleated red blood cell.

关 键 词：恶性肿瘤 贫血 全血细胞分析仪 有核红细胞 白细胞 

分 类 号：R446.113[医药卫生—诊断学]