咳喘落治疗175例哮喘临床总结  

Clinical Summarization of“Kechuanluo”in Treating 175 Patients with Asthma

作　　者：吴银根[1] 于素霞[1] 张惠勇[1] 王宏长[1] 李培成[1] 倪伟[1] 

机构地区：[1]上海中医药大学龙华医院呼吸内科,上海200032

出　　处：《上海中医药杂志》2000年第9期19-21,共3页Shanghai Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金!资助项目 (3 9670 889)

摘　　要：将 2 60例支气管哮喘急性发作期轻、中度患者 ,随机分为治疗组 (中药咳喘落 ) 175例和对照组 (氨茶碱加酮替酚 ) 85例。观察治疗前后主要症状、肺功能、白细胞介素 4、5 (IL -4、IL -5 )、免疫球蛋白和嗜酸性粒细胞阳离子蛋白等的变化。结果表明 ,治疗组显效率和总有效率分别为5 2 6%和 91 4% ,咳、痰、喘 3项主症有明显的改善 ;能显著提高哮喘患者的通气功能 (FEV1 0 %、V5 0 、V2 5 ) ,降低IgE ;并可明显降低哮喘患者血清IL -4、IL -5和ECP含量 ,其下降幅度明显大于西药对照组 ,显示出该方具有抑制气道变应性炎症 ,降低气道高反应的作用。patients with mild and moderate bronchial asthma of acute stage were randomly divided into treatment group(175 cases treated by “Kechuanluo”)and control group(85 cases treated by aminophylline and ketotifen).The main symptoms,lung function,IL-4,IL-5,immunoglobulin and positive ion protein of eosinophil were observed before and after treatment.Results showed that,in treatment group,the markedly effective rate and total effective rate were respectively 52 6% and 91 4%;symptoms about cough,phlegm and asthma were relieved obviously;FEV 1 0 %,V 50 and V 25 increased;IgE decreased;the content of serum IL-4,IL-5 and ECP reduced,and fell more than those in control group.The results revealed that“Kechuanluo” could relieve the imflammation and reduced bronchial hyperresponsiveness.

关 键 词：支气管哮喘 咳喘落 中医药疗法 通气功能 

分 类 号：R256[医药卫生—中医内科学]