糖尿病性白内障发病的有关因素研究  

STUDY OF FACTORS RELATED TO THE INCIDENCE OF CATARACT IN PATIENTS WITH NONINSUL-DEPENDENT DIABETES MELLTUS

作　　者：夏小平[1] 张晓[1] 夏海涛[2] 

机构地区：[1]中山医科大学附属第三医院,510630 [2]南昌市第一医院眼科,330008

出　　处：《江西医药》2000年第4期211-212,共2页Jiangxi Medical Journal

摘　　要：目的研究非胰岛素依赖型糖尿病（ＮＩＤＤＭ）性白内障发病的有关因素。方法对７９２例ＮＩＤＤＭ病人进行眼部和血尿检测。白内障的诊断接 Ｃｈｙｌａｃｋ等的晶体混浊分类系统 Ⅱ进行。结果本组患者中白内障的发生率为 ６２．３７％，白内障的发生与性别无关，但与糖尿病的病程有关。糖尿病病程少于５年者与大于５年者之间其白内障的发生率有显著差别；血液ＢＵＮ和／或Ｃｒ含量升高说明肾功能的损害，这些患者白内障的发生率明显高于ＢＵＮ和／或Ｃｒ含量正常的糖尿病患者。结论ＮＩＤＤＭ患者病程的延长、肾功能不良及血糖控制不良可加速白内障的发展。Objective: To investigate the factors related to the development of cataract in patients with non-insulin-dependent diabetes mellitus(NIDDM).Methods:Seven hundreds ninety two patients with NIDDM received (1)ophthal molgic examination and (2) blood and urine assay.Diagnosis of cataract was based on lens opacities classification system Ⅱ. All cases meeting 'N Ⅱ ','C Ⅱ 'or 'P Ⅱ 'level were diagnosed as cataract-Results:The incidence of cataract in this group of NIDDM was 62.37%(494/ 792), which was significantly relative to the length of the disease course, but not to sex of the patients. The occurence rate of cataract in patients with NIDDM in five years was much lower than that in those over five years. Raising concentrations of blood urea nitrogen,creatinine indicated malfunction of the kidneys,and the occurrence rate of cataract in these patients was higher. Conclusion: This study indicates that prologation of the course of NIDDM, renal dysfunction as well as poor blood gbucose control can accelerate the development of cataract in patients with NIDDM.

关 键 词：糖尿病性白内障 病因 病程 影响因素 

分 类 号：R587.2[医药卫生—内分泌] R776.102[医药卫生—内科学]