艾塞那肽治疗肥胖2型糖尿病疗效观察  

作　　者：庞敏[1] 张红军[1] 

机构地区：[1]四川广元市中心医院,628000

出　　处：《中国社区医师（医学专业）》2013年第10期143-144,共2页

摘　　要：目的:观察艾塞那肽治疗2型糖尿病的疗效。方法:将2型糖尿病患者100例随机分为治疗组50例和对照组50例。在常规服用二甲双胍基础上,治疗组予艾塞那肽皮下注射,对照组予胰岛素(诺和灵50R)皮下注射,观察疗效和不良反应。结果:艾塞那肽组的血糖控制和胰岛素组相比无显著差异,两组空腹血糖下降幅度相似,艾塞那肽对餐后血糖的控制更好;艾塞那肽对肥胖患者有控制体重增加,减轻体重作用,降低血脂,左心室内径缩小。两组均未发生严重不良反应。结论:艾塞那肽治疗2型糖尿病能有效控制血糖,并有效控制体重增加。Objective:Concept the Cha Aise that peptide efficacy of the treatment of type 2 diabetes:Type 2 diabetes patients were randomly divided into a treatment group of 50 patients,50 patients were treated.On the basis of conventional metformin treatment group to exenatide subcutaneously to insulin(Novolin 50R)subcutaneous injection of the control group,observation of efficacy and adverse reactions.Result:a the exenatide group of glycemic control and insulin groups showed no significant difference in the two sets of fasting blood glucose decline similar exenatide better postprandial glucose control;exenatide on weight control in obese patients increase the weight loss effect,lowering blood lipids,left ventricular diameter narrowing.The two groups were not serious adverse reactions.Conclusions:Exenatide treatment of type 2 diabetes can effectively control blood sugar,and effectively control weight gain.

关 键 词：艾塞那肽 2型糖尿病 疗效血糖 体重 血脂 左心室内径 

分 类 号：R587.1[医药卫生—内分泌]