2007—2012年天津医科大学第二医院口服镇静催眠药应用分析  

Analysis on The Use of Oral Sedative Hypnotics in The Second Hospital of Tianjin Medical University During 2007-2012

作　　者：齐妍[1] 黎云燕[1] 王国栋[1,2] 王莹[1] 冯博杰[1] 

机构地区：[1]天津医科大学第二医院药学部,天津300211 [2]天津医科大学基础医学院药理学系,天津300070

出　　处：《中国医院用药评价与分析》2013年第4期316-319,共4页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:了解2007—2012年我院口服镇静催眠药的使用情况及用药趋势,为临床合理用药提供依据。方法:根据我院医院信息系统(CHIS)中2007—2012年口服镇静催眠药的原始数据资料,采用世界卫生组织(WHO)推荐的限定日剂量(DDD)分析法,对各年口服镇静催眠药的销售金额、用药频度(DDDs)、限定日费用(DDC)等进行比较分析。结果:2007—2012年我院口服镇静催眠药的销售金额和DDDs基本呈增长趋势,DDC稳中有降。艾司唑仑、劳拉西泮、氯硝西泮等苯二氮类药的DDDs均较高,以唑吡坦为代表的新型非苯二氮类药用量增长迅速。结论:我院口服镇静催眠药应用基本合理,其中苯二氮类药占主导地位,新型非苯二氮类药用量也有逐年上升趋势,前景广阔。进一步加强精神药品的监督管理仍是今后工作的重点。OBJECTIVE：To analyze the status and tendency of the use of oral sedative hypnotics in our hospital from 2007 to 2012 for reference of clinical rational drug use. METHODS ：The utilization data of oral sedative hypnoticsduring 2007-2012 retrieved from hospital information system （CHIS）were analyzed contrastively regarding the consumption sum, DDDs and defined daily cost （DDC）etc using the defined daily dose （DDD）method recommended by WHO. RESULTS：The consumption sum and DDDs of the oral sedative hypnotics during 2007-2012 assumed growth trend on the whole, hut the defined daily cost （DDC）was stable with a slight decline. Benzodiazepines, such as estazolam,lorazepam and clonazepam were high in DDDs. The consumption amount of neotype non-benzodiazepines such as zolpidem increased rapidly. CONCLUSION：The use of oral sedative hypnotics in our hospital is basically rational, with benzodiazepines assuming a dominant place. The neotype non-benzodiazcpines which witnessed year-on- year increase in consumption have a broad prospect. Strengthened supervision and administration on psychotropic drugs is still the focus of our future work.

关 键 词：口服镇静催眠药 用药分析 用药频度 限定日剂量 

分 类 号：R971.3[医药卫生—药品]