北京社区卫生服务机构应用左氧氟沙星合理性分析  

Analysis of The Rationality of The Use of Levofloxacin in Beijing's Community Health Services

作　　者：陈世财[1,2] 杨悦[1] 刘宪军[2] 赵桂宏[2] 李海燕[2] 丁全[2] 张晓兰[2] 

机构地区：[1]沈阳药科大学工商管理学院,沈阳110016 [2]首都医科大学潞河教学医院/北京市通州区潞河医院药剂科,北京101100

出　　处：《中国医院用药评价与分析》2013年第4期347-350,共4页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:评价左氧氟沙星在北京社区卫生服务机构临床应用中的安全性与合理性。方法:采用回顾性方法,选取北京市19家社区卫生服务机构2011年上半年门急诊使用口服或静脉用左氧氟沙星处方9 805张,对左氧氟沙星的应用情况进行统计、分析。结果:北京社区卫生服务机构应用左氧氟沙星广泛,9 805张处方中有5 980张左氧氟沙星使用不合理,不合理现象主要表现为适应证不适宜、联合使用不适宜、配伍禁忌或不良药物相互作用等现象,个别存在不满18岁的青少年使用口服或静脉用左氧氟沙星的情况。结论:北京社区卫生服务机构左氧氟沙星的应用存在不合理现象应引起重视,以确保基层临床用药的安全性和合理性。OBJECTIVE：To evaluate the safety and rationality of the application of levofloxacin in Beijing＇ s community health services. METHODS：Retrospective method is employed in which 9 805 prescriptions of orally or intravenously administered levofloxacin given during the first half of 2011 at emergency rooms or outpatient departmentsof Beijing＇ s 19 community health services are collected to analyze the clinical application of this drug. RESULTS： Levofloxacin is widely administered at Beijing＇ s community health services. There were 5 980 irrational prescriptions in total 9 805 prescriptions. The problems with these prescriptions include inappropriate indications, unsuitable combination of drugs,incompatiability, and adverse side effects from drug interactions. The worst of all is that in some individual cases levofloxacin was even administered to patients under 18. CONCLUSION ：More attention should be paid to fact that irrational application of levofloxacin exists in Beijing＇ s community health services to ensure the safety and rationality of clinical administration of drugs by grass-roots medical staff.

关 键 词：基层社区卫生服务机构 左氧氟沙星 应用分析 合理用药 

分 类 号：R978.1[医药卫生—药品]